This week's Diabetes Bulletin...

...

Wednesday, 9 April 2008

Diabetic Medicine - Volume 25, Issue 4, April 2008 (no electronic access - paper copy available in library)

Special Report

Consensus meeting on reporting glycated haemoglobin (HbA1c) and estimated average glucose (eAG) in the UK: report to the National Director for Diabetes, Department of Health
J. H. Barth, S. M. Marshall and I. D. Watson
pages 381–382

Review Article

Clinical features, diagnosis and management of maternally inherited diabetes and deafness (MIDD) associated with the 3243A>G mitochondrial point mutation
R. Murphy, D. M. Turnbull, M. Walker and A. T. Hattersley
pages 383–399

Original Articles: Genetics

Associations between glucose tolerance, insulin sensitivity and insulin secretion phenotypes and polymorphisms in adiponectin and adiponectin receptor genes in the Quebec Family Study
S.-M. Ruchat, R. J. F. Loos, T. Rankinen, M.-C. Vohl, S. J. Weisnagel, J.-P. Després, C. Bouchard and L. Pérusse
pages 400–406

Original Articles: Complications

Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55)
R. Pradeepa, M. Rema, J. Vignesh, M. Deepa, R. Deepa and V. Mohan
pages 407–412

Thermoregulatory sudomotor dysfunction and diabetic neuropathy develop in parallel in at-risk feet
P. C. Sun, H. D. Lin, S. H. Jao, R. C. Chan, M. J. Kao and C. K. Cheng
pages 413–418

Matrix metalloproteinases and diabetic foot ulcers: the ratio of MMP-1 to TIMP-1 is a predictor of wound healing
M. Muller, C. Trocme, B. Lardy, F. Morel, S. Halimi and P. Y. Benhamou
pages 419–426

Cardiovascular risk factor management is poorer in diabetic patients with undiagnosed peripheral arterial disease than in those with known coronary heart disease or cerebrovascular disease. Results of a nationwide study in tertiary diabetes centres
J.-M. González-Clemente, J. A. Piniés, A. Calle-Pascual, Á. Saavedra, C. Sánchez, D. Bellido, T. Martín-Folgueras, I. Moraga, A. Recasens, J. Girbés, M.-Á. Sánchez-Zamorano and D. Mauricio on behalf of the PADiD Study Group
pages 427–434

Original Articles: Treatment

Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial
C. Pan, W. Yang, J. P. Barona, Y. Wang, M. Niggli, P. Mohideen, Y. Wang and J. E. Foley
pages 435–441

Long-term efficacy and safety of insulin detemir compared to Neutral Protamine Hagedorn insulin in patients with Type 1 diabetes using a treat-to-target basalbolus regimen with insulin aspart at meals: a 2-year, randomized, controlled trial
P. C. Bartley, M. Bogoev, J. Larsen and A. Philotheou
pages 442–449

Original Articles: Clinical Care and Delivery
Continuous Subcutaneous Glucose Monitoring System in diabetic mothers during labour and postnatal glucose adaptation of their infants
E. Stenninger, A. Lindqvist, J. Åman, I. Östlund and E. Schvarcz
pages 450–454

Development of alternative methods of data collection in South Asians with Type 2 diabetes
C. E. Lloyd, J. Sturt, M. Johnson, S. Mughal, G. Collins and A. H. Barnett
pages 455–462

Original Articles: Metabolism

Are family factors universally related to metabolic outcomes in adolescents with Type 1 diabetes?
F. J. Cameron, T. C. Skinner, C. E. de Beaufort, H. Hoey, P. G. F. Swift, H. Aanstoot, J. Åman, P. Martul, F. Chiarelli, D. Daneman, T. Danne, H. Dorchy, E. A. Kaprio, F. Kaufman, M. Kocova, H. B. Mortensen, P. R. Njølstad, M. Phillip, K. J. Robertson, E. J. Schoenle, T. Urakami, M. Vanelli, R. W. Ackermann, S. E. Skovlund on behalf of the Hvidoere Study Group on Childhood Diabetes
pages 463–468

Relationship between -glutamyltransferase and metabolic syndrome in a Korean population
M. Y. Lee, S. B. Koh, J. H. Koh, S. M. Nam, J. Y. Shin, Y. G. Shin, I. D. Kong, S. Y. Ryu, T. Y. Lee, J. K. Park and C. H. Chung
pages 469–475

Fatty liver is an independent risk factor for the development of Type 2 diabetes in Korean adults
C.-H. Kim, J.-Y. Park, K.-U. Lee, J.-H. Kim and H.-K. Kim
pages 476–481

Original Articles: Education/Psychological issues

The development of personal models of diabetes in the first 2 years after diagnosis: a prospective longitudinal study
V. L. Lawson, C. Bundy and J. N. Harvey
pages 482–490

Patients’ perceptions and experiences of taking oral glucose-lowering agents: a longitudinal qualitative study
J. Lawton, E. Peel, O. Parry and M. Douglas
pages 491–495

Short Reports

The North West Diabetic Pregnancy Audit: a practical system for multi-centre diabetic pregnancy audit
R. J. Young, E. M. Holmes, I. F. Casson and M. Maresh
pages 496–500

Prevalence of impaired awareness of hypoglycaemia in adults with Type 1 diabetes
J. Geddes, J. E. Schopman, N. N. Zammitt and B. M. Frier
pages 501–504

Ethnic differences in plantar pressures in diabetic patients with peripheral neuropathy
M. P. Solano, L. M. Prieto, J. C. Varon, M. Moreno and A. J. M. Boulton
pages 505–507

Letters: Correspondence

Serum uric acid, mortality and glucose control in patients with Type 2 diabetes mellitus: a PreCIS database study
D. Pitocco, F. Zaccardi, E. Di Stasio, F. Romitelli, S. A. Santini and G. Ghirlanda
pages 508–508

Comments on the letter by Pitocco et al. (Serum uric acid, mortality and glucose control in patients with Type 2 diabetes mellitus: a PreCIS database study)
A. G. Ioachimescu and B. J. Hoogwerf
pages 509–509

Letters: Original Observations

Cocaine decreases plasma insulin concentrations in non-diabetic subjects: a randomized double-blind study
D. Rott, D. D. Langleben and I. Elman
pages 510–511

Corrigendum

Corrigendum
pages 512–512

National Prescribing Centre's eCAB 29th March

BMJ: http://bmj.com/

Guidelines: Management of diabetes from preconception to the postnatal period: summary of NICE guidance http://www.bmj.com/cgi/content/full/336/7646/714

Commentary: Controversies in management of diabetes from preconception to the postnatal period http://www.bmj.com/cgi/content/full/336/7646/717

National electronic Library for Medicines (NeLM): http://www.nelm.nhs.uk

Meta-analysis: metformin may delay onset of diabetes in those at risk http://www.nelm.nhs.uk/Record%20Viewing/vR.aspx?id=591446

Once-daily basal insulin glargine vs. thrice-daily prandial insulin lispro in people with type 2 diabetes on oral hypoglycaemic agents (APOLLO study) http://www.nelm.nhs.uk/Record%20Viewing/vR.aspx?id=591541

Clinical Guidelines

Diabetes in pregnancy http://www.nice.org.uk/guidance/index.jsp?action=byID&o=11946

Diabetes vol. 57, part 3 (March 2008)

beta - Cell replication by loosening the brakes of glucagon - like peptide - 1 receptor signaling
Author(s):
Schutt , F . C . ; Drucker , D . J .
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Increasing GLP - 1 - induced beta - cell proliferation by silencing the negative regulators of signaling cAMP response element modulator - alpha and DUSP14
Author(s):
Klinger , S . ; Poussin , C . ; Debril , M . - B . ; Dolci , W . ; Halban , P . A . ; Thorens , B .
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Increased skeletal muscle tumor necrosis factor - alpha and impaired insulin signaling persist in obese women with gestational diabetes mellitus 1 year postpartum
Author(s):
Friedman , J . E . ; Kirwan , J . P . ; Jing , M . ; Presley , L . ; Catalano , P . M
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Transcription factor 7 - like 2 regulates beta - cell survival and function in human pancreatic islets
Author(s):
Shu , L . ; Sauter , N . S . ; Schulthess , F . T . ; Matveyenko , A . V . ; Oberholzer , J . ; Maedler , K .
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Page:
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Protein kinase C theta activation induces insulin - mediated constriction of muscle resistance arteries
Author(s):
Bakker , W . ; Sipkema , P . ; Stehouwer , C . D . A . ; Serne , E . H . ; Smulders , Y M . ; Van Hinsbergh , V . W . M . ; Eringa , E . C .
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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NICE updates 30 March 2008

Diabetes (type 2) - newer agents

Diabetes in pregnancy

Diabetes in pregnancy

BMJ Vol. 336, No. 7646, 29 March 2008

Renal complications of childhood type 1 diabetes
Jean-Claude Carel and Claire Levy-Marchal

Screen all pregnant women for risk factors for gestational diabetes, says NICE
Zosia Kmietowicz

Risk of microalbuminuria and progression to macroalbuminuria in a cohort with childhood onset type 1 diabetes: prospective observational study
Rakesh Amin, Barry Widmer, A Toby Prevost, Phillip Schwarze, Jason Cooper, Julie Edge, Loredana Marcovecchio, Andrew Neil, R Neil Dalton, and David B Dunger

Management of diabetes from preconception to the postnatal period: summary of NICE guidance
The Guideline Development Group

Commentary: Controversies in management of diabetes from preconception to the postnatal period
Lucy C Chappell and Sarah J Germain

NICE News 2008 - Clinical Guidelines

Diabetes in Pregnancy

National Prescribing Centre's eCAB 20 March 2008

· Optium-H blood glucose test strips for professional use manufactured by Abbott Diabetes Care http://www.mhra.gov.uk/NewsCentre/CON014400

Diabetes, Obesity and Metabolism (OnLine Early Abstracts 18th March 2008) Full text available via interlibrary loan

Original Articles

Glimepiride as insulin sensitizer: increased liver and muscle responses to insulin
R. C. T. Mori, S. M. Hirabara, A. E. Hirata, M. M. Okamoto U. F. Machado

Antidiabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation
R. R. Ortiz-Andrade, J. C. Sánchez-Salgado, G. Navarrete-Vázquez, S. P. Webster, M. Binnie, S. García-Jiménez, I. León-Rivera, P. Cigarroa-Vázquez, R. Villalobos-Molina S. Estrada-Soto
Research Letters

Effect of Panax ginseng supplementation on biomarkers of glucose tolerance, antioxidant status and oxidative stress in type 2 diabetic subjects: results of a placebo-controlled human intervention trial
S. W. Ma, I. F. F. Benzie,T. T. W. Chu, B. S. P. Fok, B. Tomlinson,L. A. H. Critchley,

Original Articles

Evidence that vildagliptin attenuates deterioration of glycaemic control during 2-year treatment of patients with type 2 diabetes and mild hyperglycaemia*
W. A. Scherbaum, A. Schweizer, A. Mari, P. M. Nilsson, G. Lalanne, Y. Wang, B. E. Dunning J. E. Foley

Metformin, but not pioglitazone, decreases postchallenge plasma ghrelin levels in type 2 diabetic patients: a possible role in weight stability?
I. Kusaka, S. Nagasaka, H. Horie S. Ishibashi

Effect of raisin consumption on oxidative stress and inflammation in obesity
J. W. Rankin, M. C. Andreae, C.-Y. Oliver Chen S. F. O’Keefe

Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes*
J. Rosenstock, S. Sankoh J. F. List

Initiation of insulin glargine therapy in type 2 diabetes subjects suboptimally controlled on oral antidiabetic agents: results from the AT.LANTUS trial*
M. Davies, F. Lavalle-González, F. Storms R. Gomis (AT.LANTUS Study Group)

Fluctuation and reproducibility of exposure and effect of insulin glargine in healthy subjects*

Implementation Science

A group randomized trial of a complexity-based organizational intervention to improve risk factors for diabetes complications in primary care settings: study protocol

By MIchael L. Parchman, Jacqueline A. Pugh, Steven D. Culler, Polly H. Noel, Nedal H. Arar, Raquel L. Romero and Raymond F. Palmer

Background: Most patients with type 2 diabetes have suboptimal control of their glucose, blood pressure (BP), and lipids - three risk factors for diabetes complications. Although the chronic care model (CCM) provides a roadmap for improving these outcomes, developing theoretically sound implementation strategies that will work across diverse primary care settings has been challenging. One explanation for this difficulty may be that most strategies do not account for the complex adaptive system (CAS) characteristics of the primary care setting. A CAS is comprised of individuals who can learn, interconnect, self-organize, and interact with their environment in a way that demonstrates non-linear dynamic behavior. One implementation strategy that may be used to leverage these properties is practice facilitation (PF). PF creates time for learning and reflection by members of the team in each clinic, improves their communication, and promotes an individualized approach to implement a strategy to improve patient outcomes. Specific objectives The specific objectives of this protocol are to: evaluate the effectiveness and sustainability of PF to improve risk factor control in patients with type 2 diabetes across a variety of primary care settings; assess the implementation of the CCM in response to the intervention; examine the relationship between communication within the practice team and the implementation of the CCM; and determine the cost of the intervention both from the perspective of the organization conducting the PF intervention and from the perspective of the primary care practice. Intervention The study will be a group randomized trial conducted in 40 primary care clinics. Data will be collected on all clinics, with 60 patients in each clinic, using a multi-method assessment process at baseline, 12, and 24 months. The intervention, PF, will consist of a series of practice improvement team meetings led by trained facilitators over 12 months. Primary hypotheses will be tested with 12-month outcome data. Sustainability of the intervention will be tested using 24 month data. Insights gained will be included in a delayed intervention conducted in control practices and evaluated in a pre-post design. Primary and secondary outcomes To test hypotheses, the unit of randomization will be the clinic. The unit of analysis will be the repeated measure of each risk factor for each patient, nested within the clinic. The repeated measure of glycosylated hemoglobin A1c will be the primary outcome, with BP and Low Density Lipoprotein (LDL) cholesterol as secondary outcomes. To study change in risk factor level, a hierarchical or random effect model will be used to account for the nesting of repeated measurement of risk factor within patients and patients within clinics. This protocol follows the CONSORT guidelines and is registered per ICMJE guidelines: Clinical Trial Registration Number: NCT00482768

Survey of diabetes specialist services 2006 - consultant survey

Survey of diabetes specialist services 2006 - consultant survey

The Association of British Clinical Diabetologists and Diabetes UK are calling for more funding and resources to improve standards of specialist diabetes care as a survey of consultant diabetologists across Britain reveals concerns about inadequate staffing levels, budget cuts, low morale and heavy workloads.(Diabetes UK - news)

Diabetic Medicine - Volume 25 Issue 4 April 2008 (no electronic access - paper copy available in library)

Letter

Comments on the letter by Pitocco et al. (Serum uric acid, mortality and glucose control in patients with Type 2 diabetes mellitus: a PreCIS database study)
A.G. Ioachimescu and B.J. Hoogwerf

Original Articles
Thermoregulatory sudomotor dysfunction and diabetic neuropathy develop in parallel in at-risk feet
P. C. Sun, H. D. Lin, S. H. Jao, R. C. Chan, M. J. Kao and C. K. Cheng

Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial
C. Pan, W. Yang, J. P. Barona, Y. Wang, M. Niggli, P. Mohideen, Y. Wang and J. E. Foley

The development of personal models of diabetes in the first 2 years after diagnosis: a prospective longitudinal study
V. L. Lawson, C. Bundy and J. N. Harvey

Cardiovascular risk factor management is poorer in diabetic patients with undiagnosed peripheral arterial disease than in those with known coronary heart disease or cerebrovascular disease. Results of a nationwide study in tertiary diabetes centres
J.-M. González-Clemente, J. A. Piniés, A. Calle-Pascual, Á. Saavedra, C. Sánchez, D. Bellido, T. Martín-Folgueras, I. Moraga, A. Recasens, J. Girbés, M.-Á. Sánchez-Zamorano and D. Mauricio on behalf of the PADiD Study Group

Letters

Lower attendance rates and higher fasting glucose levels in the month of Ramadan in patients with diabetes in a Muslim country
H. Alberti, N. Boudriga and M. Nabli

Original Articles

Health utility values associated with diabetic retinopathy
A. Lloyd, B. Nafees, S. Gavriel, M. D. Rousculp, K. S. Boye and A. Ahmad

Risk factors for diabetic retinopathy in a South Indian Type 2 diabetic populationthe Chennai Urban Rural Epidemiology Study (CURES) Eye Study 4
R. Pradeepa, B. Anitha, V. Mohan, A. Ganesan and M. Rema

Case Report

Varenicline may trigger severe hypoglycaemia in Type 1 diabetes
P. L. Kristensen, U. Pedersen-Bjergaard and B. Thorsteinsson
Original Articles

Relationship between -glutamyltransferase and metabolic syndrome in a Korean population
M. Y. Lee, S. B. Koh, J. H. Koh, S. M. Nam, J. Y. Shin, Y. G. Shin, I. D. Kong, S. Y. Ryu, T. Y. Lee, J. K. Park and C. H. Chung

Fatty liver is an independent risk factor for the development of Type 2 diabetes in Korean adults
C.-H. Kim, J.-Y. Park, K.-U. Lee, J.-H. Kim and H.-K. Kim

Should liver function tests be included in definitions of metabolic syndrome? Evidence from the association between liver function tests, components of metabolic syndrome and prevalent cardiovascular disease
M. C. Devers, S. Campbell, J. Shaw, P. Zimmet and D. Simmons

Prevalence of the diabetic foot syndrome at the primary care level in Germany: a cross-sectional study
A. Sämann, O. Tajiyeva, N. Müller, T. Tschauner, H. Hoyer, G. Wolf and U. A. Müller
Letters

Establishing pragmatic estimated glomerular filtration rate thresholds to guide metformin prescribing: careful assessment of risks and benefits is required
J. T. George and G. A. McKay

Cocaine decreases plasma insulin concentrations in non-diabetic subjects: a randomized double-blind study
D. Rott, D. D. Langleben and I. Elman

Original Articles

Six-year incidence of lower extremity arterial disease and associated risk factors in Type 1 diabetic African-Americans
M. S. Roy and B. Peng

Vibrotactile sense in median and ulnar nerve innervated fingers of men with Type 2 diabetes, normal or impaired glucose tolerance
L. B. Dahlin, S. Thrainsdottir, R. Cederlund, N. O. B. Thomsen, K. F. Eriksson, I. Rosén, T. Speidel and G. Sundqvist

NICE: Commissioning guides

Foot care service for people with diabetes

Diabetes, Obesity and Metabolism - Volume 10, Issue 4, April 2008 (full text via interlibrary loan)

Review Articles

The contribution of ApoB and ApoA1 measurements to cardiovascular risk assessment
M. Andrikoula I. F. W. McDowell
pages 271–278

A cardiologist view of vascular disease in diabetes
Christopher J. Lockhart, Paul K. Hamilton, Katherine A. McVeigh Gary E. McVeigh
pages 279–292

Original Articles

The dipeptidyl peptidase-4 inhibitor PHX1149 improves blood glucose control in patients with type 2 diabetes mellitus
G. Garcia-Soria, G. Gonzalez-Galvez, G. M. Argoud, M. Gerstman, T. W. Littlejohn III, S. L. Schwartz, A.-M. O’Farrell, X. Li, J. M. Cherrington, C. Bennett H.-P. Guler
pages 293–300

Combination of the insulin sensitizer, pioglitazone, and the long-acting GLP-1 human analog, liraglutide, exerts potent synergistic glucose-lowering efficacy in severely diabetic ZDF rats
P. J. Larsen, E. M. Wulff, C. F. Gotfredsen, C. L. Brand, J. Sturis, N. Vrang,L. B. Knudsen K. Lykkegaard
pages 301–311

Thiazolidinedione insulin sensitizers and the heart: a tale of two organs?
R. E. Buckingham A. Hanna
pages 312–328

Continuous subcutaneous insulin infusion leads to immediate, stable and long-term changes in metabolic control
I. Aberle, D. Zimprich, B. Bach-Kliegel, C. Fischer, M. Gorny, A. Kliegel, K. Langer M. Kliegel
pages 329–335

Daily administration of the GIP-R antagonist (Pro3)GIP in streptozotocin-induced diabetes suggests that insulin-dependent mechanisms are critical to antiobesity-diabetes actions of (Pro3)GIP
P. L. McClean, V. A. Gault, N. Irwin, J. T. McCluskey P. R. Flatt
pages 336–342

PEGylation improves the hypoglycaemic efficacy of intranasally administered glucagon-like peptide-1 in type 2 diabetic db/db mice
Y. S. Youn, J. E. Jeon, S. Y. Chae, S. Lee K. C. Lee
pages 343–346

Research Letters

Resveratrol blocks high glucoseinduced mitochondrial reactive oxygen species production in bovine aortic endothelial cells: role of phase 2 enzyme induction?
C. Lu, I. F. Bambang, J. S. Armstrong, M. Whiteman
pages 347–349

No differences in mortality between users of pancreatic-specific and non-pancreatic-specific sulphonylureas: a cohort analysis
Josie M. M. Evans, Simon A. Ogston, Frank Reimann, Fiona M. Gribble, Andrew D. Morris Ewan R. Pearson
pages 350–352

National Prescribing Centre eCAB Week in Review (29 February 2008)

Diabetes-related complications, glycaemic control and falls in older adults http://www.nelm.nhs.uk/Record%20Viewing/vR.aspx?id=590727

Diabetes - insulin pump therapy (final appraisal determination) http://www.nice.org.uk/guidance/index.jsp?action=folder&o=39807

Diabetes Vol 57 ; Part 3 (March 2008)

Comment on : Tritt et al . ( 2007 ) Functional Waning of Naturally Occurring CD4 + Regulatory T - cells Contributes to the Onset of Autoimmune Diabetes : Diabetes 57 : 113 - 123 , 2007
Author(s):
David C . Thomas
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Response to Comment on : Tritt et al . ( 2007 ) Functional Waning of Naturally Occurring CD4 + Regulatory T - Cells Contributes to the Onset of Autoimmune Diabetes : Diabetes 57 : 113 - 123 , 2007
Author(s):
Michael Tritt
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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First - Trimester Human Fetal Pancreas Transplantation for Type 1 Diabetes Treatment : An Alternative Approach for Achieving Long - Term Graft Survival ?
Author(s):
Georgia Fousteri
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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HLA on Chromosome 6 : The Story Gets Longer and Longer
Author(s):
Leslie J . Raffel
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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ß - Cell Replication by Loosening the Brakes of Glucagon - Like Peptide - 1 Receptor Signaling
Author(s):
Frans C . Schuit
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Rho Kinase Inhibition : A New Approach for Treating Diabetic Nephropathy ?
Author(s):
Leon A . Bach
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Interaction Between Exercise and Leptin in the Treatment of Obesity
Author(s):
Christopher Morrison
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Retinal Arteriolar Narrowing Predicts Incidence of Diabetes : The Australian Diabetes , Obesity and Lifestyle ( AusDiab ) Study
Author(s):
Thanh T . Nguyen
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Insulin Signaling Stimulates Insulin Transport by Bovine Aortic Endothelial Cells
Author(s):
Hong Wang
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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The Role of Free - Living Daily Walking in Human Weight Gain and Obesity
Author(s):
James A . Levine
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Insulin Internalizes GLUT2 in the Enterocytes of Healthy but Not Insulin - Resistant Mice
Author(s):
Vanessa Tobin
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Forkhead Transcription Factor FoxO1 in Adipose Tissue Regulates Energy Storage and Expenditure
Author(s):
Jun Nakae
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Resistin Impairs Insulin - Evoked Vasodilation
Author(s):
Maria Teresa Gentile
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Increasing GLP - 1 - Induced ß - Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator - &agr ; and DUSP14
Author(s):
Sonia Klinger
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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A Central Role for Neuronal AMP - Activated Protein Kinase ( AMPK ) and Mammalian Target of Rapamycin ( mTOR ) in High - Protein Diet - Induced Weight Loss
Author(s):
Eduardo R . Ropelle
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Increased Skeletal Muscle Tumor Necrosis Factor - &agr ; and Impaired Insulin Signaling Persist in Obese Women With Gestational Diabetes Mellitus 1 Year Postpartum
Author(s):
Jacob E . Friedman
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Synergy Between Leptin Therapy and a Seemingly Negligible Amount of Voluntary Wheel Running Prevents Progression of Dietary Obesity in Leptin - Resistant Rats
Author(s):
Alexandra Shapiro
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Evidence of an Influence of a Polymorphism Near the INSIG2 on Weight Loss During a Lifestyle Intervention in Obese Children and Adolescents
Author(s):
Thomas Reinehr
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Reduced Immunogenicity of First - Trimester Human Fetal Pancreas
Author(s):
Kerstin Brands
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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The Repression of IRS2 Gene by ATF3 , a Stress - Inducible Gene , Contributes to Pancreatic ß - Cell Apoptosis
Author(s):
Dan Li
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Transcription Factor 7 - Like 2 Regulates ß - Cell Survival and Function in Human Pancreatic Islets
Author(s):
Luan Shu
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Defining Pancreatic Endocrine Precursors and Their Descendants
Author(s):
Peter White
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Postnatal Programming of Glucocorticoid Metabolism in Rats Modulates High - Fat Diet - Induced Regulation of Visceral Adipose Tissue Glucocorticoid Exposure and Sensitivity and Adiponectin and Proinflammatory Adipokines Gene Expression in Adulthood
Author(s):
Sandrine Boullu - Ciocca
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Predictors of Incretin Concentrations in Subjects With Normal , Impaired , and Diabetic Glucose Tolerance
Author(s):
Kirsten Vollmer
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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The Effect of Cyclooxygenase - 2 Inhibition on Renal Hemodynamic Function in Humans With Type 1 Diabetes
Author(s):
David Z . I . Cherney
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Acute Metformin Therapy Confers Cardioprotection Against Myocardial Infarction Via AMPK - eNOS - Mediated Signaling
Author(s):
John W . Calvert
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Protein Kinase C &thgr ; Activation Induces Insulin - Mediated Constriction of Muscle Resistance Arteries
Author(s):
Wineke Bakker
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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706 - 713
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Targeting of RhoA / ROCK Signaling Ameliorates Progression of Diabetic Nephropathy Independent of Glucose Control
Author(s):
Vasantha Kolavennu
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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In Vitro Hyperglycemia or a Diabetic Intrauterine Environment Reduces Neonatal Endothelial Colony - Forming Cell Numbers and Function
Author(s):
David A . Ingram
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Delayed Recovery of Cognitive Function Following Hypoglycemia in Adults With Type 1 Diabetes : Effect of Impaired Awareness of Hypoglycemia
Author(s):
Nicola N . Zammitt
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Therapeutic Potential of Peroxisome Proliferators - Activated Receptor - &agr ; / &ggr ; Dual Agonist With Alleviation of Endoplasmic Reticulum Stress for the Treatment of Diabetes
Author(s):
Kyu Lee Han
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Different Brain Responses to Hypoglycemia Induced by Equipotent Doses of the Long - Acting Insulin Analog Detemir and Human Regular Insulin in Humans
Author(s):
Paolo Rossetti
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Reversal of Streptozotocin - Induced Diabetes in Mice by Cellular Transduction With Recombinant Pancreatic Transcription Factor Pancreatic Duodenal Homeobox - 1 : A Novel Protein Transduction Domain - Based Therapy
Author(s):
Vijay Koya
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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757 - 769
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Analysis of Single Nucleotide Polymorphisms Identifies Major Type 1A Diabetes Locus Telomeric of the Major Histocompatibility Complex
Author(s):
Theresa A . Aly
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Genetic Variation and Association Analyses of the Nuclear Respiratory Factor 1 ( nRF1 ) Gene in Chinese Patients With Type 2 Diabetes
Author(s):
Yang Liu
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Identification and Replication of a Novel Obesity Locus on Chromosome 1q24 in Isolated Populations of Cilento
Author(s):
Marina Ciullo
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Association of CDKAL1 , IGF2BP2 , CDKN2A / B , HHEX , SLC30A8 , and KCNJ11 With Susceptibility to Type 2 Diabetes in a Japanese Population
Author(s):
Shintaro Omori
ISSUE:
2008 ; VOL 57 ; PART 3 (2008-March)
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Diabetes Care 2008, vol. 31, part 3 (March 2008) 

The Rosigliazone Meta - Analysis : Lessons for the future
Jonathan J . Shuster
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e10 - e10
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Dramatic Improvement of Subcutaneous Insulin Resistance with Nafamostat Ointment Treatment
Satoshi Kawashima
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e11 - e11
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BMI May Be Better Than Waist Circumference for Defining Metabolic Syndrome in Japanese Women
Masaru Sakurai
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e12 - e12
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Diabetic Ketoacidosis : the Usual Villain or a Scapegoat ? : A novel cause of severe metabolic acidosis in type 1 diabetes
Paul Lee
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e13 - e13
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Routine Psychological Screening in Youth With Type 1 Diabetes and Their Parents : a Notion Whose Time Has Come ? : Response to Cameron et al
Maartje de Wit
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e14 - e14
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Routine Psychological Screening in Youth With Type 1 Diabetes and Their Parents : a Notion Whose Time Has Come ? : Response to de Wit and Snoek
Fergus Cameron
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e15 - e15
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Comparison of Pharmacokinetics and Dynamics of the Long - Acting Insulin Analogs Glargine and Detemir at Steady State in Type 1 Diabetes : a Double - Blind , Randomized , Crossover Study : Response to Porcellati et al
Salomon Banarer
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Comparison of Pharmacokinetics and Dynamics of the Long - Acting Insulin Analogs Glargine and Detemir at Steady State in Type 1 Diabetes : a Double - Blind , Randomized , Crossover Study : Response to Banarer
Francesca Porcellati
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e17 - e17
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Bloodletting Ameliorates Insulin Sensitivity and Secretion in Parallel to Reducing Liver Iron in Carriers of HFE Gene Mutations : Response to Equitani et al .
Luca Valenti
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e18 - e18
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Bloodletting Ameliorates Insulin Sensitivity and Secretion in Parallel to Reducing Liver Iron in Carriers of HFE Gene Mutations : Response to Valenti et al
Melania Manco
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e19 - e19
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Relationship of A1C to Glucose Concentrations in Children With Type 1 Diabetes : Assessments by high - frequency glucose determinations by sensors
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Clinical Predictors of Disease Progression and Medication Initiation in Untreated Patients With Type 2 Diabetes and A1C Less Than 7 %
Lydie Nkwimi Pani
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386 - 390
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Diabetes - Related Complications , Glycemic Control , and Falls in Older Adults
Ann V . Schwartz
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391 - 396
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Association Between Serum Bioavailable Testosterone Concentration and the Ratio of Glycated Albumin to Glycated Hemoglobin in Men With Type 2 Diabetes
Michiaki Fukui
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397 - 401
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Short - Term Effects of an Educational Program on Health - Seeking Behavior for Infections in Patients With Type 2 Diabetes : A randomized controlled intervention trial in primary care
Leonie M . A . J . Venmans
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402 - 407
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Spanish Diabetes Self - Management With and Without Automated Telephone Reinforcement : Two randomized trials
Kate Lorig
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408 - 414
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Insulin Restriction and Associated Morbidity and Mortality in Women with Type 1 Diabetes
Ann E . Goebel - Fabbri
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415 - 419
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Elevated Depression Symptoms , Antidepressant Medicine Use , and Risk of Developing Diabetes During the Diabetes Prevention Program
Richard R . Rubin
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420 - 426
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Stress Burden and Diabetes in Two American Indian Reservation Communities
Luohua Jiang
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427 - 429
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Factors Affecting Use of Insulin Pens by Patients With Type 2 Diabetes
Richard R . Rubin
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430 - 432
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Reevaluating the Digital Divide : Current Lack of Internet Use Is Not a Barrier to Adoption of Novel Health Information Technology
Alice J . Watson
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433 - 435
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Metabolic and Immunological Features of the Failing Islet - Transplanted Patient
Paolo Fiorina
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436 - 438
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Time to Insulin Initiation Cannot Be Used in Defining Latent Autoimmune Diabetes in Adults
Sinead Brophy
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439 - 441
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Human Insulin Analog - Induced Lipoatrophy
Ximena Lopez
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442 - 444
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Effect of LDL Cholesterol and Treatment With Losartan on End - Stage Renal Disease in the RENAAL Study
Andrew M . Tershakovec
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Is a Failure to Recognize an Increase in Food Intake a Key to Understanding Insulin - Induced Weight Gain ?
Miriam Ryan
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Improving the Comparability of Diabetes Mortality Statistics in the U . S . and Mexico
Christopher J . L . Murray
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451 - 458
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Diabetes - and Nondiabetes - Related Lower Extremity Amputation Incidence Before and After the Introduction of Better Organized Diabetes Foot Care : Continuous longitudinal monitoring using a standard method
Ronan J . Canavan
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459 - 463
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Prevalence of Polyneuropathy in Pre - Diabetes and Diabetes Is Associated With Abdominal Obesity and Macroangiopathy : The MONICA / KORA Augsburg Surveys S2 and S3
Dan Ziegler
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464 - 469
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Breast - Feeding and Type 2 Diabetes in the Youth of Three Ethnic Groups : The SEARCH for Diabetes in Youth Case - Control Study
Elizabeth J . Mayer - Davis
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470 - 475
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Associations Between Diabetes and Clinical Markers of Benign Prostatic Hyperplasia Among Community - Dwelling Black and White Men
Aruna V . Sarma
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476 - 482
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Evidence of a Relationship Between Infant Birth Weight and Later Diabetes and Impaired Glucose Regulation in a Chinese Population
Xinhua Xiao
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483 - 487
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Plasma Glucose Regulation and Mortality in Pima Indians
Nan Hee Kim
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488 - 492
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Relationship of Glycemic Control , Exogenous Insulin , and C - Peptide Levels to Ischemic Heart Disease Mortality Over a 16 - Year Period in People With Older - Onset Diabetes : The Wisconsin Epidemiologic Study of Diabetic Retinopathy ( WESDR )
Flavio E . Hirai
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493 - 497
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Incidence and Determinants of Carpal Tunnel Decompression Surgery in Type 2 Diabetes : The Fremantle Diabetes Study
Ashley Makepeace
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498 - 500
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Influence of Elevated Cardiometabolic Risk Factor Levels on Treatment Changes in Type 2 Diabetes
Jaco Voorham
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Coffee Consumption Is Associated With Higher Plasma Adiponectin Concentrations in Women With or Without Type 2 Diabetes : A prospective cohort study
Catherine J . Williams
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504 - 507
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Are Primary Care Physicians More Likely to Record Diabetes on Death Certificates ?
Laura N . McEwen
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508 - 510
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Trends and Disparities in U . S . Emergency Department Visits for Hypoglycemia , 1993 - 2005
Adit A . Ginde
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511 - 513
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Cognitive Function in Children and Subsequent Type 2 Diabetes
Gunilla M . Olsson
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514 - 516
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Skin Autofluorescence : A tool to identify type 2 diabetic patients at risk for developing microvascular complications
Esther G . Gerrits
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Page:517 - 521
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Multi - Site Testing With a Point - of - Care Nerve Conduction Device Can Be Used in an Algorithm to Diagnose Diabetic Sensorimotor Polyneuropathy
Bruce A . Perkins
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522 - 524
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FreeStyle Navigator Continuous Glucose Monitoring System Use in Children With Type 1 Diabetes Using Glargine - Based Multiple Daily Dose Regimens : Results of a pilot trial Diabetes Research in Children Network ( DirecNet ) Study Group
Stuart Weinzimer
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525 - 527
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A Risk Score for Type 1 Diabetes Derived From Autoantibody - Positive Participants in the Diabetes Prevention Trial - Type 1
Jay M . Sosenko
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528 - 533
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The Protein Tyrosine Phosphatase Nonreceptor 22 ( PTPN22 ) Is Associated With High GAD Antibody Titer in Latent Autoimmune Diabetes in Adults : Non Insulin Requiring Autoimmune Diabetes ( NIRAD ) Study 3
Antonio Petrone
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534 - 538
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Effect of Aging on Glucose Homeostasis : Accelerated deterioration of ß - cell function in individuals with impaired glucose tolerance
Ervin Szoke
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539 - 543
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Relationship of Retinal Vascular Caliber With Diabetes and Retinopathy : The Multi - Ethnic Study of Atherosclerosis ( MESA )
Thanh Tan Nguyen
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544 - 549
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A Prospective Study of Cardiorespiratory Fitness and Risk of Type 2 Diabetes in Women
Cognitive Function in Children and Subsequent Type 2 Diabetes

Xuemei Sui
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550 - 555
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Prediction of Mortality Using Measures of Cardiac Autonomic Dysfunction in the Diabetic and Nondiabetic Population : The MONICA / KORA Augsburg Cohort Study
Dan Ziegler
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556 - 561
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Should Nonalcoholic Fatty Liver Disease Be Included in the Definition of Metabolic Syndrome ? : A cross - sectional comparison with Adult Treatment Panel III criteria in nonobese nondiabetic subjects
Giovanni Musso
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562 - 568
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Objectively Measured Time Spent Sedentary Is Associated With Insulin Resistance Independent of Overall and Central Body Fat in 9 - to 10 - Year - Old Portuguese Children
Luis B . Sardinha
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569 - 575
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Overweight Latino Children and Adolescents Have Marked Endothelial Dysfunction and Subclinical Vascular Inflammation in Association With Excess Body Fat and Insulin Resistance
A . Enrique Caballero
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576 - 582
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Underweight as a Predictor of Diabetes in Older Adults : A large cohort study
Toshimi Sairenchi
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583 - 584
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Quantifying the Excess Risk of Type 2 Diabetes by Body Habitus Measurements Among Australian Aborigines Living in Remote Areas
Srinivas Kondalsamy - Chennakesavan
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Prevalence of the Metabolic Syndrome Among U . S . Adolescents Using the Definition From the International Diabetes Federation
Earl S . Ford
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Optimal Cut Points of Waist Circumference for the Clinical Diagnosis of Metabolic Syndrome in the Japanese Population
Yuka Matoba
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Osteoprotegerin , Thiazolidinediones Treatment , and Silent Myocardial Ischemia in Type 2 Diabetic Patients
Ariane Sultan
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Economic Costs of Diabetes in the U . S . in 2007
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Diabetic Neuropathy
Zachary T . Bloomgarden
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Should We Screen for Risk of Type 1 Diabetes ?
Mikael Knip
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The Economic Imperative to Conquer Diabetes
Judith Fradkin
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