BIG 4 diabetes articles in the last fortnight

-We have full text access to BMJ, NEJM and JAMA
-Full text access to The Lancet is available two months after publication. Articles published within the last two months are available via interlibrary loan

The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study
...type 2 diabetes in people with impaired glucose tolerance, but how long these benefits extend beyond the period of active intervention, and whether such interventions reduce the risk of cardiovascular disease (CVD) and mortality, is unclear. We aimed to assess whether intensive lifestyle interventions have a long-term effect on the risk of diabe...
The Lancet - 10:20 AM (48 minutes ago)

Enhanced diabetes care to patients of south Asian ethnic origin (the United Kingdom Asian Diabetes Study): a cluster randomised controlled trial
...type 2 diabetes.
The Lancet - 10:20 AM (48 minutes ago)

Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies
...type 2 diabetes mellitus have increased cardiovascular disease risk compared with those without diabetes. Treatment of the residual risk, other than blood pressure and LDL-cholesterol control, remains important as the rate of diabetes increases worldwide. The accelerated atherosclerosis and cardiovascular disease in diabetes is likely to be mult...
The Lancet - 10:20 AM (48 minutes ago)

Diabetes care for south Asian patients: a special case
...type 2 diabetes is rising rapidly worldwide, particularly for south Asian people living in urban areas. South Asian individuals have a four-fold to six-fold greater risk of developing type 2 diabetes, contract the disease at an earlier age, and have higher rates of renal and cardiovascular complications than do other ethnic groups. Although prev...
The Lancet - 10:20 AM (48 minutes ago)

Lifestyle intervention, diabetes, and cardiovascular disease
...type 2 diabetes was first proposed in 1921 by Elliot Joslin who wrote: “There are entirely too many diabetic patients in the country…Therefore, it is proper at the present time to devote attention not alone to treatment, but still more, as in the campaign against the typhoid fever, to prevention. The results may not be quite so striking or as im...
The Lancet - 10:20 AM (48 minutes ago)

Halting the accelerating epidemic of type 1 diabetes
...type 1 diabetes has been steadily increasing worldwide since the middle of the 20th century. The increase has so far been linear and predictable. However, in today's Lancet Valma Harjutsalo and colleagues show that in Finland, which has the highest incidence of type 1 diabetes in the world, the incidence predicted for 2010 on the basis of data f...
The Lancet - 10:20 AM (48 minutes ago)

Profile: Jean Claude Mbanya: fighting diabetes in Africa
...advocates for diabetes in Africa, almost ended up as a chemical engineer. As he prepared to graduate from high school in Cameroon, Mbanya had a scholarship in hand to study chemical engineering in the USA. But at the urging of his father—a local chief who had diabetes and had long dreamed of becoming a doctor—Mbanya went to the capital city, to ...
The Lancet - 10:20 AM (48 minutes ago)

Book: A meeting point for cardiologists and diabetologists
...years for diabetes. Heart disease accounts for between two-thirds and three-quarters of all deaths in type 2 diabetes, and is the leading cause of death in type 1, not least because it abolishes the premenopausal protection from coronary disease enjoyed by women. 30 years ago, these effects attracted less attention: a coronary epidemic was sweep...
The Lancet - 10:20 AM (48 minutes ago)

Statins and diabetes – Authors' reply
...people with diabetes whose baseline LDL cholesterol concentration was 2·6 mmol/L or less. As previously reported, reducing LDL cholesterol with statin therapy by a further 1 mmol/L in this group resulted in a significant 32% relative reduction in the incidence of major vascular events (136 [9·8%] vs 170 [12·2%], rate ratio 0·68; p=0·02, webfigur...
The Lancet - 10:20 AM (48 minutes ago)

Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study
...type 1 diabetes worldwide, reaching 40 per 100 000 people per year in the 1990s. Our aim was to assess the temporal trend in type 1 diabetes incidence since 2000 in Finnish children aged younger than 15 years and to predict the number of cases of type 1 diabetes in the future.
The Lancet - 10:20 AM (48 minutes ago)

Statins and diabetes
...patients with diabetes (Jan 12, p 117) raises the question as to whether all patients with diabetes should be on statins.
The Lancet - 10:20 AM (48 minutes ago)

The global challenge of diabetes
...annual American Diabetes Association Scientific Sessions taking place between June 6–10 in San Francisco, much of the focus in this week's Lancet is on the link between diabetes mellitus and heart disease.
The Lancet - 10:20 AM (48 minutes ago)

Type 1 diabetes, hyperglycaemia, and the heart
...Type 1 diabetes is associated with a substantially increased risk of cardiovascular disease that might not always be appreciated in view of the fairly young age of patients with this condition. In fact, in type 1 diabetes, the heart is subject to a variety of pathological insults, including accelerated atherosclerosis, cardiac autonomic neuropat...
The Lancet - 10:20 AM (48 minutes ago)

Intensive insulin therapy in newly diagnosed type 2 diabetes
...type 2 diabetes is characterised by worsening hyperglycaemia and progressive deterioration in function of the insulin-secreting pancreatic β cells. Despite intense investigative efforts, the pathophysiological basis underlying β-cell dysfunction (and the concomitant loss of β-cell mass) remains unclear. Nevertheless, the central importance of de...
The Lancet - 10:20 AM (48 minutes ago)

Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial
...type 2 diabetes might improve β-cell function and result in extended glycaemic remissions. We did a multicentre, randomised trial to compare the effects of transient intensive insulin therapy (continuous subcutaneous insulin infusion [CSII] or multiple daily insulin injections [MDI]) with oral hypoglycaemic agents on β-cell function and diabetes...
The Lancet - 10:20 AM (48 minutes ago)

[EDITORIALS] Self monitoring of blood glucose in type 2 diabetes
BMJ current issue - 11:56 PM (11 hours ago)

[RESEARCH] Different strategies for screening and prevention of type 2 diabetes in adults: cost effectiveness analysis
...type 2 diabetes: (a) screening for type 2 diabetes to enable early detection and treatment, (b) screening for type 2 diabetes and impaired glucose tolerance, intervening with lifestyle interventions in those with a diagnosis of impaired glucose tolerance to delay or prevent diabetes, (c) as for (b) but with pharmacological interventions, and (d)...
BMJ current issue - 11:56 PM (11 hours ago)

[RESEARCH] Efficacy of self monitoring of blood glucose in patients with newly diagnosed type 2 diabetes (ESMON study): randomised controlled trial
...type 2 diabetes mellitus. Design Prospective randomised controlled trial of self monitoring versus no monitoring (control). Setting Hospital diabetes clinics. Participants 184 (111 men) people aged <70 class="entry-source-title-link" href="http://www.google.com/reader/view/feed/http://www.bmj.com/rss/current.xml" target="_blank" closure_hashcode_="295">BMJ current issue - 11:56 PM (11 hours ago)

[EDITORIALS] Screening for and prevention of type 2 diabetes
BMJ current issue - 11:56 PM (11 hours ago)

[RESEARCH] Cost effectiveness of self monitoring of blood glucose in patients with non-insulin treated type 2 diabetes: economic evaluation of data from the DiGEM trial
...type 2 diabetes. Design Incremental cost utility analysis from a healthcare perspective. Data on resource use from the randomised controlled diabetes glycaemic education and monitoring (DiGEM) trial covered 12 months before baseline and 12 months of trial follow-up. Quality of life was measured at baseline and 12 months using the EuroQol EQ-5D q...
BMJ current issue - 11:56 PM (11 hours ago)

CORRESPONDENCE: Multifactorial Intervention and Mortality in Type 2 Diabetes
To the Editor: In their article on aggressive multiagent treatment of risk factors for diabetic complications, Gæde et al. (Feb. ...
New England Journal of Medicine - May 21, 2008 (2 days ago)

ORIGINAL CONTRIBUTION: Association Between Circulating Oxidized Low-Density Lipoprotein and Incidence of the Metabolic Syndrome
Context Experimental data support the hypothesis that oxidized low-density lipoprotein (LDL) is associated with the metabolic syndrome. However, this hypothesis has not been tested in humans. Objective To establish the relation of oxidized LDL with metabolic syndrome in the general community. Design, Setting, and Participants The Coronary Artery...
JAMA current issue - May 20, 2008 (3 days ago)

LETTERS: Surgical vs Behavioral Therapy for Weight Loss in Patients With Type 2 Diabetes
JAMA current issue - May 13, 2008 9:27 PM

LETTERS: Surgical vs Behavioral Therapy for Weight Loss in Patients With Type 2 Diabetes--Reply
JAMA current issue - May 13, 2008 9:27 PM

[NEWS] Prevalence of pre-existing diabetes in pregnancy doubled in seven years in a Californian population
BMJ current issue - May 8, 2008 11:40 PM