This week's Diabetes Bulletin...

...

Friday, 29 August 2008

Recent Big 4 diabetes articles

[Department of Error] Department of Error
...type 2 diabetes on oral hypoglycaemic agents (APOLLO): an open randomised controlled trial. Lancet 2008; 371: 1073–84—In this Article (March 29), the fifth line from the bottom of the panel (p 1075) should have read: “≤5·5 mmol/L: no further titration”. The second sentence of the footnote to table 2 (p 1079) should have read: “Fasting blood gluc...
The Lancet - 10:40 (1 hour ago)


[Correspondence] Intensive insulin therapy in patients with type 2 diabetes – Authors' reply
...latent autoimmune diabetes in adults in our population. Although there is no formal consensus regarding diagnostic criteria, the disorder is generally defined as GAD antibody positivity in adult diabetic patients who do not initially (for at least 6 months) require insulin. Usually patients with latent autoimmune diabetes have a low body-mass in...
The Lancet - 10:40 (1 hour ago)


[Correspondence] Intensive insulin therapy in patients with type 2 diabetes
...type 2 diabetes (May 24, p 1573) is an exciting prospect.
The Lancet - 10:40 (1 hour ago)


[Correspondence] Intensive insulin therapy in patients with type 2 diabetes
Jianping Weng and colleagues are to be commended for building a concept that could change clinical practice. However, their conclusions need some clarification.
The Lancet - 10:40 (1 hour ago)


CORRESPONDENCE: Widespread Amyloid Deposition in Transplanted Human Pancreatic Islets
...type 1 diabetes mellitus, diagnosed at 16 years of age, in ...
New England Journal of Medicine - 27 Aug 2008 (2 days ago)



CARING FOR THE CRITICALLY ILL PATIENT: Benefits and Risks of Tight Glucose Control in Critically Ill Adults: A Meta-analysis
...The American Diabetes Association and Surviving Sepsis Campaign recommend tight glucose control in critically ill patients based largely on 1 trial that shows decreased mortality in a surgical intensive care unit. Because similar studies report conflicting results and tight glucose control can cause dangerous hypoglycemia, the data underlying th...
JAMA current issue - 26 Aug 2008 (3 days ago)


[RESEARCH] Role of blood pressure in development of early retinopathy in adolescents with type 1 diabetes: prospective cohort study
...type 1 diabetes. Design Prospective cohort study. Setting Diabetes Complications Assessment Service at the Children’s Hospital at Westmead, Sydney, Australia. Participants 1869 patients with type 1 diabetes (54% female) screened for retinopathy with baseline median age 13.4 (interquartile range 12.0-15.2) years, duration 4.9 (3.1-7.0) years, and...
BMJ current issue - 26 Aug 2008 (3 days ago)


[EDITORIALS] Complications of type 1 diabetes in adolescents
BMJ current issue - 26 Aug 2008 (3 days ago)


[NEWS] Diabetes care needs to focus more on ethnic inequalities, say experts
BMJ current issue - 22 Aug 2008 16:46

[PRACTICE] Should we prescribe diuretics for patients with prediabetes and hypertension?
BMJ current issue - 21 Aug 2008 14:44


LETTERS: Insulin Therapy and Lipid Overload in Type 2 Diabetes--Reply
JAMA current issue - 19 Aug 2008 21:44

LETTERS: Insulin Therapy and Lipid Overload in Type 2 Diabetes
JAMA current issue - 19 Aug 2008 21:44

LETTERS: Pioglitazone vs Glimepiride in the PERISCOPE Trial
JAMA current issue - 19 Aug 2008 21:44


EDITORIAL: Environmental Arsenic Exposure and Diabetes
JAMA current issue - 19 Aug 2008 21:44

LETTERS: Pioglitazone vs Glimepiride in the PERISCOPE Trial--Reply
JAMA current issue - 19 Aug 2008 21:44



LETTERS: Pioglitazone vs Glimepiride in the PERISCOPE Trial
JAMA current issue - 19 Aug 2008 21:44


LETTERS: Insulin Therapy and Lipid Overload in Type 2 Diabetes
JAMA current issue - 19 Aug 2008 21:44


PRELIMINARY COMMUNICATION: Arsenic Exposure and Prevalence of Type 2 Diabetes in US Adults
...related to diabetes development, but the effect of exposure to low to moderate levels of inorganic arsenic on diabetes risk is unknown. In contrast, arsenobetaine, an organic arsenic compound derived from seafood intake, is considered nontoxic. Objective To investigate the association of arsenic exposure, as measured in urine, with the prevalen...
JAMA current issue - 19 Aug 2008 21:44

[Seminar] Acute myocardial infarction
...epidemic of diabetes and obesity in the developed world and the transition from infectious diseases to cardiovascular disease in the developing world will place an increasing demand on health-care infrastructures required to deliver time-dependent and resource-intensive care. This Seminar discusses the underlying pathophysiology, evolving perspe...
The Lancet - 15 Aug 2008 11:00

[Articles] Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial
...or with diabetes with end-organ damage.
The Lancet - 15 Aug 2008 11:00

CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 25-2008 -- A 43-Year-Old Man with Fatigue and Lesions in the Pituitary and Cerebellum
...Diabetes insipidus, hypogonadism, and hypothyroidism had developed beginning 9 years earlier, and lesions had been detected in the region of the pituitary stalk and in the cerebellum. He was treated with glucocorticoids for suspected neurosarcoidosis, but fatigue, ataxia, and neurologic symptoms worsened. Computed tomography of the chest and abd...
New England Journal of Medicine - 13 Aug 2008 22:25

[CORRECTIONS] Evidence shows higher long term risks from gestational diabetes
BMJ current issue - 6 Aug 2008 17:36

Basal insulin glargine vs prandial insulin lispro in type 2 diabetes
Reinhard Bretzel and colleagues (March 29, p 1073) compared once-daily insulin glargine with thrice-daily prandial insulin lispro as add-on therapy to continued oral hypoglycaemic agents. Although glycosylated haemoglobin did not differ between regimens, the overall incidence of hypoglycaemic events was four times higher with insulin lispro than wi...
The Lancet - 1 Aug 2008 11:15

Basal insulin glargine vs prandial insulin lispro in type 2 diabetes – Authors' reply
Sabine Arnolds and Klaus Rave state that the higher hypoglycaemic rate in the lispro group than in the glargine group was potentiated by the presence of glimepiride. However, the relative frequencies of hypoglycaemic events by hour of day showed a similar distribution profile, with peaks at 2 pm for lispro and 3 pm for glargine. A further explanati...
The Lancet - 1 Aug 2008 11:15

Department of Health (DH) Publication

Five years on: delivering the diabetes national service framework http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_087123

NICE guidance updates

The following guidance matching your health area preferences has been published or updated:

Diabetes (type 2) - newer agents
Diabetes - insulin pump therapy
Diabetes - type 2 (update)
Type 1 diabetes
Diabetes - type 2 (update)

Diabetes Care Vol 31; Part 8; August 2008

We have full text access to these articles. Click here to access the journal. You will need an NHS Athens password to access the full text of articles.


Evaluation of a System for Automatic Detection of Diabetic Retinopathy From Color Fundus Photographs in a Large Population of Patients With Diabetes : Response to Abrà ; moff et al .
Author(s):John A . Olson
Page:
e63 - e63

Evaluation of a System for Automatic Detection of Diabetic Retinopathy From Color Fundus Photographs in a Large Population of Patients With Diabetes : Response to Olson et al .
Author(s):Michael D . Abrà ; moff
Page:
e64 - e64

Translating the A1C Assay Into Estimated Average Glucose Values
Author(s):David M . Nathan
Page:
1473 - 1478

Colesevelam HCl Improves Glycemic Control and Reduces LDL Cholesterol in Patients With Inadequately Controlled Type 2 Diabetes on Sulfonylurea - Based Therapy
Author(s):Vivian A . Fonseca
Page:
1479 - 1484

Influence of and Optimal Insulin Therapy for a Low - Glycemic Index Meal in Children With Type 1 Diabetes Receiving Intensive Insulin Therapy
Author(s):Rochelle L . Ryan
Page:
1485 - 1490

Optimizing Postprandial Glycemia in Pediatric Patients With Type 1 Diabetes Using Insulin Pump Therapy : Impact of glycemic index and prandial bolus type
Author(s):Michele A . O'Connell
Page:
1491 - 1495

Clinical Application of 1 , 5 - Anhydroglucitol Measurements in Patients with Hepatocyte Nuclear Factor - 1&agr ; Maturity - Onset Diabetes of the Young
Author(s):Jan Skupien
Page:
1496 - 1501

Hemodynamic Effects of Fenofibrate and Coenzyme Q10 in Type 2 Diabetic Subjects With Left Ventricular Diastolic Dysfunction
Author(s):Gerard T . Chew
Page:
1502 - 1509

Cost - Effectiveness of Intensified Versus Conventional Multifactorial Intervention in Type 2 Diabetes : Results and projections from the Steno - 2 study
Author(s):Peter Gæ ; de
Page:
1510 - 1515

Diabetes Complications in Youth : Qualitative analysis of parents` perspectives of family learning and knowledge
Author(s):
Lisa M . Buckloh
Page:
1516 - 1520

Monitoring and Discussing Health - Related Quality of Life in Adolescents With Type 1 Diabetes Improve Psychosocial Well - Being : A randomized controlled trial
Author(s):Maartje de Wit
Page:
1521 - 1526

Blood Glucose Awareness Training Delivered Over the Internet
Author(s):Daniel Cox
Page:
1527 - 1528

Evaluation of a Systems Navigator Model for Transition From Pediatric to Adult Care for Young Adults With Type 1 Diabetes
Author(s):Norma Van Walleghem
Page:
1529 - 1530

Impaired Chronotropic Response to Exercise Stress Testing in Patients With Diabetes Predicts Future Cardiovascular Events
Author(s):P . Michael Ho
Page:
1531 - 1533

Association of 1 , 5 - Anhydroglucitol and 2 - h Postprandial Blood Glucose in Type 2 Diabetic Patients
Author(s):
Christoph Stettler
Page:
1534 - 1535

Risks of Nontraumatic Lower - Extremity Amputations in Patients with Type 1 Diabetes : A population - based cohort study in Sweden
Author(s):
Junmei Miao Jonasson
Page:
1536 - 1540

Diabetes , Glycemic Control , and Risk of Hospitalization With Pneumonia : A population - based case - control study
Author(s):
Jette B . Kornum
Page:
1541 - 1545

The Rising Incidence of Type 1 Diabetes Is Accounted for by Cases With Lower - Risk Human Leukocyte Antigen Genotypes
Author(s):
Spiros Fourlanos
Page:
1546 - 1549

Insulin Sensitivity Measured With Euglycemic Clamp Is Independently Associated With Glomerular Filtration Rate in a Community - Based Cohort
Author(s):
Elisabet Nerpin
Page:
1550 - 1555

Economic Benefits of Intensive Insulin Therapy in Critically Ill Patients : The Targeted Insulin Therapy to Improve Hospital Outcomes ( TRIUMPH ) Project
Author(s):
Archana R . Sadhu
Page:
1556 - 1561

Health Care Use and Costs Associated With Use of a Health Club Membership Benefit in Older Adults with Diabetes
Author(s):
Huong Q . Nguyen
Page:
1562 - 1567

Dietary Patterns and A1C in Japanese Men and Women
Author(s):
Akiko Nanri
Page:
1568 - 1573

Increased Risk of Diabetes and Polychlorinated Biphenyls and Dioxins : A 24 - year follow - up study of the Yucheng cohort
Author(s):
Shu - Li Wang
Page:
1574 - 1579

Sexual Dysfunction in Jordanian Diabetic Women
Author(s):
Ruba M . Abu Ali
Page:
1580 - 1581

Lifetime Risk of Cardiovascular Disease Among Individuals With and Without Diabetes Stratified by Obesity Status in the Framingham Heart Study
Author(s):
Caroline S . Fox
Page:
1582 - 1584

Association Between p . Leu54Met Polymorphism at the Paraoxonase - 1 Gene and Plantar Fascia Thickness in Young Subjects With Type 1 Diabetes
Author(s):
Patricia H . Gallego
Page:
1585 - 1589

Hyperglycemia Is Associated With Enhanced Thrombin Formation , Platelet Activation , and Fibrin Clot Resistance to Lysis in Patients With Acute Coronary Syndrome
Author(s):
Anetta Undas
Page:
1590 - 1595

Diminished Alveolar Microvascular Reserves in Type 2 Diabetes Reflect Systemic Microangiopathy
Author(s):
William W . Chance
Page:
1596 - 1601

GAD65 Autoantibody Responses in Japanese Latent Autoimmune Diabetes in Adult Patients
Author(s):
Taro Maruyama
Page:
1602 - 1607

Differences in the Contribution of the CTLA4 Gene to Susceptibility to Fulminant and Type 1A Diabetes in Japanese Patients
Author(s):
Eiji Kawasaki
Page:
1608 - 1610

Epidermal Innervation in Type 1 Diabetic Patients : A 2 . 5 - year prospective study after simultaneous pancreas / kidney transplantation
Author(s):
Petr Boucek
Page:
1611 - 1612

Short - Term Hyperglycemic Dysregulation in Patients With Type 1 Diabetes Does Not Change Myocardial Triglyceride Content or Myocardial Function
Author(s):
Sebastiaan Hammer
Page:
1613 - 1614

Serum Bilirubin and Ferritin Levels Link Heme Oxygenase - 1 Gene Promoter Polymorphism and Susceptibility to Coronary Artery Disease in Diabetic Patients
Author(s):
Ying - Hwa Chen
Page:
1615 - 1620

Association of Acculturation Levels and Prevalence of Diabetes in the Multi - Ethnic Study of Atherosclerosis ( MESA )
Author(s):
Namratha R . Kandula
Page:
1621 - 1628

Preventing Left Ventricular Hypertrophy by ACE Inhibition in Hypertensive Patients With Type 2 Diabetes : A prespecified analysis of the Bergamo Nephrologic Diabetes Complications Trial ( BENEDICT )
Author(s):
Piero Ruggenenti
Page:
1629 - 1634

Dysglycemia and a History of Reproductive Risk Factors
Author(s):
Sarah D . McDonald
Page:
1635 - 1638

Risk of Glucose Intolerance and Diabetes in Hemipancreatectomized Donors Selected for Normal Preoperative Glucose Metabolism
Author(s):
Anjali F . Kumar
Page:
1639 - 1643

Increased Daily Walking Improves Lipid Oxidation Without Changes in Mitochondrial Function in Type 2 Diabetes
Author(s):
Michael I . Trenell
Page:
1644 - 1649

One - Hour Plasma Glucose Concentration and the Metabolic Syndrome Identify Subjects at High Risk for Future Type 2 Diabetes
Author(s):
Muhammad A . Abdul - Ghani
Page:
1650 - 1655

Dose - Dependent Effect of Rosuvastatin on VLDL - Apolipoprotein C - III Kinetics in the Metabolic Syndrome
Author(s):
Esther M . M . Ooi
Page:
1656 - 1661

Sex - Specific Association of the Putative Fructose Transporter SLC2A9 Variants With Uric Acid Levels Is Modified by BMI
Author(s):
Anita Br and stä ; tter
Page:
1662 - 1667

Increased Risk of Cardiovascular Disease in Young Women Following Gestational Diabetes Mellitus
Author(s):
Baiju R . Shah
Page:
1668 - 1669

Validation of Prediction of Diabetes by the Archimedes Model and Comparison With Other Predicting Models
Author(s):
Michael Stern
Page:
1670 - 1671

Is the Combination of Sulfonylureas and Metformin Associated With an Increased Risk of Cardiovascular Disease or All - Cause Mortality ? : A meta - analysis of observational studies
Author(s):
Ajay D . Rao
Page:
1672 - 1678

Comprehensive Foot Examination and Risk Assessment : A report of the Task Force of the Foot Care Interest Group of the American Diabetes Association , with endorsement by the American Association of Clinical Endocrinologists
Author(s):
Andrew J . M . Boulton
Page:
1679 - 1685

The Impact of Prevention on Reducing the Burden of Cardiovascular Disease
Author(s):
Richard Kahn
Page:
1686 - 1696

Approaches to Treatment of Type 2 Diabetes
Author(s):
Zachary T . Bloomgarden
Page:
1697 - 1703

Translating the A1C Assay
Author(s):
Richard Kahn
Page:
1704 - 1707

Reducing Cardiovascular Disease : Opportunities and consequences
Author(s):
Peter J . Neumann
Page:
1708 - 1709

Friday, 1 August 2008

Big 4 Diabetes articles

Access
BMJ - current paper copy in library, electronic access 3 months delay - NHS Athens
Lancet - electronic access 2 months delay - NHS Athens
JAMA - current electronic access - NHS Athens
NEJM - current paper copy in library, partial electronic access to recent articles - no password
full text electronic access - 3 months delay - NHS Athens

HEALTH AGENCIES UPDATE: Pesticides-Diabetes Link
JAMA current issue - 22 Jul 2008 21:34

EDITORIAL: Diabetes Mellitus--A Call for Papers
JAMA current issue - 22 Jul 2008 21:34

LETTERS: Oral Hypoglycemic Use and the SANDS Trial
JAMA current issue - 22 Jul 2008 21:34

COMMENTARY: Heart Failure With Preserved Ejection Fraction: Treat Now by Treating Comorbidities
JAMA current issue - 22 Jul 2008 21:34

LETTERS: Oral Hypoglycemic Use and the SANDS Trial--Reply
JAMA current issue - 22 Jul 2008 21:34

HEALTH AGENCIES UPDATE: Drugs and Cancer Risk
JAMA current issue - 22 Jul 2008 21:34

Statins for children?
...hypertension or diabetes, and those whose family history is unknown should also be screened.
The Lancet - 18 Jul 2008 10:44

BOOK REVIEW: Controversies in Treating Diabetes: Clinical and Research Aspects
Shortly before his election as president, John F. Kennedy wrote, "Let us welcome controversial books and controversial authors." To this statement we might add "and books on controversial medical topics," ...
New England Journal of Medicine - 16 Jul 2008 22:27

ORIGINAL CONTRIBUTION: Fetuin-A and Incident Diabetes Mellitus in Older Persons
...type 2 diabetes mellitus is unknown. Objective To determine whether fetuin-A levels are associated with incident diabetes in older persons. Design, Setting, and Participants Observational study among 3075 well-functioning persons aged 70 to 79 years. In this case-cohort study, we retrospectively measured fetuin-A levels in baseline serum among...
JAMA current issue - 8 Jul 2008 21:39

β-cell transplantation for diabetes therapy
In their Comment, Piero Ruggenenti and colleagues outline why they have decided not to continue islet-cell transplantation. We wish to clarify several points for readers.
The Lancet - 4 Jul 2008 10:48

β-cell transplantation for diabetes therapy – Authors' reply
In the largest series of islet transplant recipients treated with a common protocol of islet preparation and post-transplantation care (the Edmonton protocol), only 16 of 36 patients were still insulin-independent at 1 year; 10 had complete graft loss. Consistently, comparative studies have found that only 31% of islet recipients versus 96% of whol...
The Lancet - 4 Jul 2008 10:

β-cell transplantation for diabetes therapy
...treatment of diabetes.
The Lancet - 4 Jul 2008 10:48

β-cell transplantation for diabetes therapy
Piero Ruggenenti and colleagues (March 15, p 883) highlight their failure to establish a clinical islet transplantation programme. Results of islet transplantation are similar to those of the early days of organ transplantation, where initial success rarely met with long-term function. The Edmonton protocol achieved reproducible insulin independenc...
The Lancet - 4 Jul 2008 10:48

CORRECTIONS: Metformin versus Insulin for the Treatment of Gestational Diabetes
...of Gestational Diabetes . In the abstract (page 2003), under Results, the parenthetical information should read "(relative risk, 0.99; 95% confidence interval, 0.80 to ...
New England Journal of Medicine - 2 Jul 2008 22:20

Diabetes Vol 57, Part 7, 2008

We have full text access to this journal. Click here and login using NHS Athens

Protein kinase C function in muscle , liver , and beta - cells and its therapeutic implications for type 2 diabetes
Author(s):Schmitz - Peiffer , C . ; Biden , T . J .
ISSUE:2008 ; VOL 57 ; PART 7 (2008-July)
Page:1774-1783

Plasma C5 glucose - to - ^ 2H ~ 2O ratio does not provide an accurate assessment of gluconeogenesis during hyperinsulinemic - euglycemic clamps in either nondiabetic or diabetic humans
Author(s):Basu , R . ; Chandramouli , V . ; Dicke , B . ; Landau , B . R . ; Rizza , R . A
ISSUE:2008 ; VOL 57 ; PART 7 (2008-July)
Page:1800-1804

Blockade of alpha 4 integrin signaling ameliorates the metabolic consequences of high - fat diet - induced obesity
Author(s):Feral , C . C . ; Neels , J . G . ; Kummer , C . ; Slepak , M . ; Olefsky , J . M . ; Ginsberg , M . H .
ISSUE:2008 ; VOL 57 ; PART 7 (2008-July)
Page:1842-1851

Diabetes Care Vol 31, Part 7, 2008

We have full text access to this journal using NHS Athens. Click here to access.

Tumor necrosis factor - alpha antagonism improves vasodilation during hyperinsulinemia in metabolic syndrome
Author(s):Tesauro , M . ; Schinzari , F . ; Rovella , V . ; Melina , D . ; Mores , N . ; Barini , A . ; Mettimano , M . ; Lauro , D . ; Iantorno , M . ; Quon , M . J
ISSUE:2008 ; VOL 31 ; PART 7 (2008-July)
Page:1439-1441

Meta - Analysis Rosiglitazone and risk of cancer : a meta - analysis of randomized clinical trials
Author(s):Monami , M . ; Lamanna , C . ; Marchionni , N . ; Mannucci , E .
ISSUE:2008 ; VOL 31 ; PART 7 (2008-July)
Page:1455-1460

Perspectives on the News Approaches to treatment of pre - diabetes and obesity and promising new approaches to type 2 diabetes
Author(s):Bloomgarden , Z . T
ISSUE:2008 ; VOL 31 ; PART 7 (2008-July)
Page:1461-1466

Editorial Death to carbohydrate counting ?
Author(s):Davis , N . J . ; Wylie - Rosett , J .
ISSUE:2008 ; VOL 31 ; PART 7 (2008-July)
Page:1467-1468

NICE updates

The following guidance matching your health area preferences has been published or updated:

Diabetes - insulin pump therapy
Diabetes - insulin pump therapy
Diabetes in pregnancy

National Prescribing Centre's 'Week in Review' 4/7/08

NPCi Blog http://www.npci.org.uk/blog/
· MeReC Rapid Review: Is aliskiren plus losartan renoprotective in patients with type 2 diabetes and nephropathy? http://www.npci.org.uk/blog/?p=160

InfoPOEMs: http://www.essentialevidenceplus.com/
· Metformin effective for gestational diabetes http://www.essentialevidenceplus.com/infopoems/dailyInfoPOEM.cfm?view=121866

National electronic Library for Medicines (NeLM): http://www.nelm.nhs.uk
· FDA panel says diabetes drugs need cardiovascular risk studies http://www.nelm.nhs.uk/Record%20Viewing/vR.aspx?id=594929

Friday, 18 July 2008

Latest Diabetes articles in the Big 4

BOOK REVIEW: Controversies in Treating Diabetes: Clinical and Research Aspects
Shortly before his election as president, John F. Kennedy wrote, "Let us welcome controversial books and controversial authors." To this statement we might add "and books on controversial medical topics," ...
New England Journal of Medicine - Jul 16, 2008 (2 days ago)

ORIGINAL CONTRIBUTION: Fetuin-A and Incident Diabetes Mellitus in Older Persons
...type 2 diabetes mellitus is unknown. Objective To determine whether fetuin-A levels are associated with incident diabetes in older persons. Design, Setting, and Participants Observational study among 3075 well-functioning persons aged 70 to 79 years. In this case-cohort study, we retrospectively measured fetuin-A levels in baseline serum among...
JAMA current issue - Jul 8, 2008 9:39 PM

β-cell transplantation for diabetes therapy
In their Comment, Piero Ruggenenti and colleagues outline why they have decided not to continue islet-cell transplantation. We wish to clarify several points for readers.
The Lancet - Jul 4, 2008 10:48 AM

β-cell transplantation for diabetes therapy – Authors' reply
In the largest series of islet transplant recipients treated with a common protocol of islet preparation and post-transplantation care (the Edmonton protocol), only 16 of 36 patients were still insulin-independent at 1 year; 10 had complete graft loss. Consistently, comparative studies have found that only 31% of islet recipients versus 96% of whol...
The Lancet - Jul 4, 2008 10:48 AM

β-cell transplantation for diabetes therapy
...treatment of diabetes.
The Lancet - Jul 4, 2008 10:48 AM

β-cell transplantation for diabetes therapy
Piero Ruggenenti and colleagues (March 15, p 883) highlight their failure to establish a clinical islet transplantation programme. Results of islet transplantation are similar to those of the early days of organ transplantation, where initial success rarely met with long-term function. The Edmonton protocol achieved reproducible insulin independenc...
The Lancet - Jul 4, 2008 10:48 AM

CORRECTIONS: Metformin versus Insulin for the Treatment of Gestational Diabetes
...of Gestational Diabetes . In the abstract (page 2003), under Results, the parenthetical information should read "(relative risk, 0.99; 95% confidence interval, 0.80 to ...
New England Journal of Medicine - Jul 2, 2008 10:20 PM

Book: Handle with care
...Primary Care Diabetes Society conference. I wanted to know more about the disease that, according to the 2002 report by Sir Derek Wanless, threatens to bankrupt the UK's National Health Service (NHS) over the next decade. It already costs the NHS more than £1 billion a year, most of which can be put down to failures in prevention and management ...
The Lancet - Jun 27, 2008 10:17 AM

Chronic kidney disease in Asia
...such as diabetes, hypertension, and metabolic syndrome, have become common and, as a result, chronic kidney disease has become a prevalent comorbidity in the past 10 years.
The Lancet - Jun 27, 2008 10:17 AM

Type 2 diabetes: pathogenesis and treatment
...type 2 diabetes mellitus, several important developments have taken place. Further evidence that the disease has a strong hereditary component led to a vigorous search to identify candidate genes (). This approach uncovered two prevalent polymorphisms (in addition to PPARy and KCNJ11). HNF1B (MODY5) bears a polymorphism associated with type 2 di...
The Lancet - Jun 27, 2008 10:17 AM

[RESEARCH] Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2
...type 2 diabetes, renal disease, atrial fibrillation, and rheumatoid arthritis. Results The validation statistics indicated that QRISK2 had improved discrimination and calibration compared with the modified Framingham score. The QRISK2 algorithm explained 43% of the variation in women and 38% in men compared with 39% and 35%, respectively, by the...
BMJ current issue - Jun 27, 2008 12:09 AM

Latest Diabetes News from the National Library for Health

MeReC Monthly (June 2008): Self-monitoring in type 2 diabetes
via NeLM news - Diabetes on 7/7/08
The latest edition of MeReC Monthly reviews the use of routine self-monitoring of blood glucose (SMBG), noting that two recent studies (ESMON and DiGEM economic analysis) have reinforced the view that it is unlikely to be beneficial in patients with type 2 diabetes who are not treated with insulin and may worsen quality of life and waste NHS resources. Therefore it should be reserved for patients treated with insulin and for non-insulin treated patients in specific circumstances, as recommended in recent NICE guidance on type 2 diabetes (see link).

SMC accepts restricted use of Eucreas tablets (vildagliptin 50mg + metformin 850mg or 1000mg) for type 2 diabetes
via NeLM news - Diabetes 7/7/08
Following a review of an abbreviated submission (used for new formulations at same or lesser cost, and new tablet strength or size), the Scottish Medicines Consortium (SMC) has accepted for restricted use within NHS Scotland, Eucreas® tablets (vildagliptin 50mg/metformin 850mg and vildagliptin 50mg /metformin 1000mg). ...

Meta-analysis: Pregabalin for painful diabetic neuropathy
via NeLM news - Diabetes on 6/7/08
Pregabalin is effective for treatment of painful diabetic neuropathy across its usual dose range, according to a meta-analysis sponsored by the drug's manufacturer and part-authored by company employees. A number of controlled trials have been carried out with pregabalin in patients with painful diabetic neuropathy, however they have used different dose regimens: this analysis was carried out to evaluate the drug's efficacy and safety in this condition at all effective doses....

DTB: exenatide (Byetta), sitagliptin (Januvia), and vildagliptin (Galvus) for type 2 diabetes
via NeLM news - Diabetes on 6/7/08
The July edition of the Drug and Therapeutics Bulletin (DTB) features a review of three new treatments for type 2 diabetes: exenatide (Byetta®), sitagliptin (Januvia®), and vildagliptin (Galvus®). It discusses the incretins and glucose metabolism, examines the trial data and its limitations, and looks at national guidelines....

FDA panel says diabetes drugs need cardiovascular risk studies
via NeLM news - Diabetes on 2/7/08
PharmaTimes reports that the US Food and Drug Administration’s (FDA) Endocrinologic and Metabolic Drugs Advisory Committee has advised US regulators they should insist that studies on new diabetes treatments include much more data on the potential heart risks of the treatments....

FDA to consider necessity of cardiovascular studies for diabetes drugs
via NeLM news - Diabetes on 30/6/08
According to a report in the Wall Street Journal, the US FDA is summoning a panel of experts to consider whether pharmaceutical companies should be required to study the cardiovascular effects of diabetes drugs prior to approval. The report points out that cardiovascular endpoints are relatively rare and therefore large, long-term studies would be required to demonstrate any statistically significant effects; this could slow the development of new drugs and would increase costs.

FDA approves PrandiMet (repaglinide and metformin) for type 2 diabetes
via NeLM news - Diabetes on 24/6/08
According to BioSpace, the FDA has approved PrandiMet™ (repaglinide and metformin) tablets as an adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes mellitus who are already treated with a meglitinide [the drug class that repaglinide belongs to] and metformin or who have inadequate glycaemic control on a meglitinide alone or metformin alone. Please see the link above for details.

Benefits of intensive glucose control in older type 2 diabetics limited by co-morbidity
via NeLM news - Diabetes on 30/6/08
A decision analysis study suggests that for older patients with type 2 diabetes, intensive blood glucose control becomes less useful with increasing co-morbidity and functional impairment; chronological age alone, however, was not useful for predicting benefit. Intensive control of blood glucose has been shown to be beneficial in type 1 diabetes, and may also improve outcomes in type 2 diabetes....

25 June 2008 - My life
via NLH Diabetes Specialist Library Whats New by Diane Clay on 25/6/08
How to manage your diabetes as a young adult, moving away from home, taking control of your life


NPC iblog: Putting blood glucose control in type 2 diabetes into perspective
via NeLM news - Diabetes on 16/6/08
The National Prescribing Centre have published an iblog discussing a “Perspective” article published in the New England Journal of Medicine, that discusses the implications of ACCORD and ADVANCE studies, alongside some other major clinical studies that evaluated the benefits of reducing risk factors, such as blood lipids, blood pressure and blood glucose levels on preventing cardiovascular (CV) disease....

Antipsychotic agents and diabetes: meta-analysis plus study data on aripiprazole
via NeLM news - Diabetes by nelm@gstt.nhs.uk on 15/6/08
Second-generation antipsychotic drugs are associated with a small increase in risk of diabetes compared to first-generation drugs, according to a meta-analysis, although retrospective analysis of data from a clinical trial suggests that an increased risk with aripiprazole may be less likely....

15 June 2008 - Interesting new diabetes papers April 2008
via NLH Diabetes Specialist Library Whats New on 15/6/08
The latest edition of Dr Roger Gadsbys bulletin is now available

11 June 2008 - Diabetic retinopathy screening
via NLH Diabetes Specialist Library Whats New on 11/6/08
Statement published by the Department of Health on 3 April 2008

11 June 2008 - Joint Position Statement - Integrated Care in the Reforming NHS
via NLH Diabetes Specialist Library Whats New on 11/6/08
A joint publication by Diabetes UK, the Association of British Clinical Diabetologists (ABCD), the Primary Care Diabetes Society (PCDS), Community Diabetes Consultants (CDC) and the RCN Diabetes Nursing Forum issued in December 2007

Diabetes, Vol 57, Part 6 

We have full text to this journal - click on here to access the journal online. You will need your Athens password to sign in.


A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K^+channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults
Author(s):Tarasov , A . I . ; Nicolson , T . J . ; Riveline , J . - P . ; Taneja , T . K . ; Baldwin , S . A . ; Baldwin , J . M . ; Charpentier , G . ; Gautier , J . - F . ; Froguel , P . ; Vaxillaire , M .
ISSUE:2008 ; VOL 57 ; PART 6
Page:
1595-1604


Critical roles for macrophages in islet angiogenesis and maintenance during pancreatic degeneration

Author(s):Tessem , J . S . ; Jensen , J . N . ; Pelli , H . ; Dai , X . - M . ; Zong , X . - H . ; Stanley , E . R . ; Jensen , J . ; Degregori , J .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1605-1617


Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion
Author(s):Braun , M . ; Ramracheya , R . ; Bengtsson , M . ; Zhang , Q . ; Karanauskaite , J . ; Partridge , C . ; Johnson , P . R . ; Rorsman , P .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1618-1628


Elevated epidermal growth factor receptor phosphorylation induces resistance artery dysfunction in diabetic db/db mice
Author(s):Belmadani , S . ; Palen , D . I . ; Gonzalez - Villalobos , R . A . ; Boulares , H . A . ; Matrougui , K .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1629-1637


beta-Cell dysfunction in subjects with impaired glucose tolerance and early type 2 diabetes: comparison of surrogate markers with first-phase insulin secretion from an intravenous glucose tolerance test
Author(s):Festa , A . ; Williams , K . ; Hanley , A . J . G . ; Haffner , S . M .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1638-1644

Retinal and cerebral microvascular signs and diabetes: the Age, Gene/Environment Susceptibility-Reykjavik Study
Author(s):Qiu , C . ; Cotch , M . F . ; Sigurdsson , S . ; Garcia , M . ; Klein , R . ; Jonasson , F . ; Klein , B . E . K . ; Eiriksdottir , G . ; Harris , T . B . ; Van Buchem , M . A .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1645-1650

Suppressors of cytokine-signaling proteins induce insulin resistance in the retina and promote survival of retinal cells
Author(s):Liu , X . ; Mameza , M . G . ; Lee , Y . S . ; Eseonu , C . I . ; Yu , C . - R . ; Derwent , J . J . K . ; Egwuagu , C . E .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1651-1658

Persistent hyperinsulinemic hypoglycemia and maturity-onset diabetes of the young due to heterozygous HNF4A mutations
Author(s):Kapoor , R . R . ; Locke , J . ; Colclough , K . ; Wales , J . ; Conn , J . J . ; Hattersley , A . T . ; Ellard , S . ; Hussain , K .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1659-1663

Distal degenerative sensory neuropathy in a long-term type 2 diabetes rat model
Author(s):Brussee , V . ; Guo , G . ; Dong , Y . ; Cheng , C . ; Martinez , J . A . ; Smith , D . ; Glazner , G . W . ; Fernyhough , P . ; Zochodne , D . W .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1664-1673

Decreased lipoprotein clearance is responsible for increased cholesterol in LDL receptor knockout mice with streptozotocin-induced diabetes
Author(s):Goldberg , L . J . ; Hu , Y . ; Noh , H . - L . ; Wei , J . ; Huggins , L . A . ; Rackmill , M . G . ; Hamai , H . ; Reid , B . N . ; Blaner , W . S . ; Huang , L . - S .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1674-1682

RhoA/Rho-kinase contribute to the pathogenesis of diabetic renal disease
Author(s):Peng , F . ; Wu , D ; Gao , B . ; Ingram , A . J . ; Zhang , B . ; Chorneyko , K . ; McKenzie , R . ; Krepinsky , J . C .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1683-1692


Abnormal muscle spindle innervation and large-fiber neuropathy in diabetic mice
Author(s):Muller , K . A . ; Ryals , J . M . ; Feldman , E . L . ; Wright , D . E .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1693-1701

Haptoglobin genotype: a determinant of cardiovascular complication risk in type 1 diabetes
Author(s):Costacou , T . ; Ferrell , R . E . ; Orchard , T . J .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1702-1706


Having one kidney does not accelerate the rate of development of diabetic nephropathy lesions in type 1 diabetic patients
Author(s):Chang , S . ; Caramori , M . L . ; Moriya , R . ; Mauer , M .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1707-1711


Urinary Smad1 is a novel marker to predict later onset of mesangial matrix expansion in diabetic nephropathy
Author(s):Mima , A . ; Arai , H . ; Matsubara , T . ; Abe , H . ; Nagai , K . ; Tamura , Y . ; Torikoshi , K . ; Araki , M . ; Kanamori , H . ; Takahashi , T
ISSUE:2008 ; VOL 57 ; PART 6
Page:1712-1722

Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats
Author(s):Han , S . ; Hagan , D . L . ; Taylor , J . R . ; Xin , L . ; Meng , W . ; Biller , S . A . ; Wetterau , J . R . ; Washburn , W . N . ; Whaley , J . M .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1723-1729

PTPN22 Trp^ 6^ 2^ 0 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes
Author(s):Smyth , D . J . ; Cooper , J . D . ; Howson , J . M . M . ; Walker , N . M . ; Plagnol , V ; Stevens , H . ; Clayton , D . G . ; Todd , J . A .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1730-1737


Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes
Author(s):Holmkvist , J . ; Almgren , P . ; Lyssenko , V . ; Lindgren , C . M . ; Eriksson , K . - F ; Isomaa , B . ; Tuomi , T . ; Nilsson , P . ; Groop , L .
ISSUE:2008 ; VOL 57 ; PART 6
Page:1738-1744


The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of HNF4A isoforms from the P1 promoter during fetal development
Author(s):Harries , L . W . ; Locke , J . M . ; Shields , B . ; Hanley , N . A . ; Hanley , K . P . ; Steele , A . ; Njolstad , P . R . ; Ellard , S . ; Hattersley , A . T
ISSUE:2008 ; VOL 57 ; PART 6
Page:
1745-1752


Sequencing-based genotyping and association analysis of the MICA and MICB genes in type 1 diabetes

Author(s):Field , S . F . ; Nejentsev , S . ; Walker , N . M . ; Howson , J . M . M . ; Godfrey , L M . ; Jolley , J . D . ; Hardy , M . P . A . ; Todd , J . A
ISSUE:2008 ; VOL 57 ; PART 6
Page:1753-1756

Friday, 11 July 2008

Diabetes Care

Diabetes Care is available free to NHS staff 3 months after publication. Articles with links provided are available earlier. You can also order individual articles using the Inter-Library Loan system if you need them quicker. Please contact the library for further details.

Volume 31, Number 7

Clinical Care/Education/Nutrition/Psychosocial Research

Isolated Hyperglycemia at 1 Hour on Oral Glucose Tolerance Test in Pregnancy Resembles Gestational Diabetes Mellitus in Predicting Postpartum Metabolic Dysfunction
Ravi Retnakaran, Ying Qi, Mathew Sermer, Philip W. Connelly, Bernard Zinman, and Anthony J.G. Hanley

Effect of Supervised Progressive Resistance-Exercise Training Protocol on Insulin Sensitivity, Glycemia, Lipids, and Body Composition in Asian Indians With Type 2 Diabetes
Anoop Misra, Narendra K. Alappan, Naval K. Vikram, Kashish Goel, Nidhi Gupta, Kanchan Mittal, Suryaprakash Bhatt, and Kalpana Luthra

Long-Term Outcome and Disability of Diabetic Patients Hospitalized for Diabetic Foot Ulcers: A 6.5-year follow-up study
Edouard Ghanassia, Laetitia Villon, Jean-François Thuan dit Dieudonné, Catherine Boegner, Antoine Avignon, and Ariane Sultan

The Prospective Contribution of Hostility Characteristics to High Fasting Glucose Levels: The moderating role of marital status
Biing-Jiun Shen, Amanda J. Countryman, Avron Spiro, III, and Raymond Niaura

Weight Loss Strategies Associated With BMI in Overweight Adults With Type 2 Diabetes at Entry Into the Look AHEAD (Action for Health in Diabetes) Trial
Hollie A. Raynor, Robert W. Jeffery, Andrea M. Ruggiero, Jeanne M. Clark, Linda M. Delahanty for the Look AHEAD (Action for Health in Diabetes) Research Group

Adjust to Target in Type 2 Diabetes: Comparison of a simple algorithm with carbohydrate counting for adjustment of mealtime insulin glulisine
Richard M. Bergenstal, Mary Johnson, Margaret A. Powers, Alan Wynne, Aleksandra Vlajnic, Priscilla Hollander, and Marc Rendell

Intake of Fruit, Vegetables, and Fruit Juices and Risk of Diabetes in Women
Lydia A. Bazzano, Tricia Y. Li, Kamudi J. Joshipura, and Frank B. Hu

Dietary Behaviors Predict Glycemic Control in Youth With Type 1 Diabetes
Sanjeev N. Mehta, Lisa K. Volkening, Barbara J. Anderson, Tonja Nansel, Jill Weissberg-Benchell, Tim Wysocki, Lori M.B. Laffel for the Family Management of Childhood Diabetes Study Steering Committee

Long-Term Follow-Up of Oral Glucose Tolerance Test–Derived Glucose Tolerance and Insulin Secretion and Insulin Sensitivity Indexes in Subjects With Glucokinase Mutations (MODY2)
Delphine Martin, Christine Bellanné-Chantelot, Inge Deschamps, Philippe Froguel, Jean-Jacques Robert, and Gilberto Velho

Improving Treatment of Depression Among Latinos With Diabetes Using Project Dulce and IMPACT
Todd P. Gilmer, Chris Walker, Elizabeth D. Johnson, Athena Philis-Tsimikas, and Jürgen Unützer

Randomized Efficacy Trial of Early Preconception Counseling for Diabetic Teens (READY-Girls)
Denise Charron-Prochownik, Margaret Ferons-Hannan, Susan Sereika, and Dorothy Becker

Epidemiology/Health Services Research

Association Between Renal Failure and Foot Ulcer or Lower-Extremity Amputation in Patients With Diabetes
David J. Margolis, Ole Hofstad, and Harold I. Feldman

Trends in Diabetes, High Cholesterol, and Hypertension in Chronic Kidney Disease Among U.S. Adults: 1988–1994 to 1999–2004
Caroline S. Fox and Paul Muntner

Dietary Patterns, Insulin Resistance, and Incidence of Type 2 Diabetes in the Whitehall II Study
Sarah A. McNaughton, Gita D. Mishra, and Eric J. Brunner

Longitudinal Association of Glucose Metabolism With Retinopathy: Results from the Australian Diabetes Obesity and Lifestyle (AusDiab) study
Robyn J. Tapp, Gabriella Tikellis, Tien Y. Wong, C. Alex Harper, Paul Z. Zimmet, Jonathan E. Shaw on behalf of the Australian Diabetes Obesity and Lifestyle Study Group

Plasma Carotenoids and Onset of Dysglycemia in an Elderly Population: Results of the Epidemiology of Vascular Ageing Study
Tasnime N. Akbaraly, Annick Fontbonne, Alain Favier, and Claudine Berr

Relationship Between Risk Factors and Mortality in Type 1 Diabetic Patients in Europe: The EURODIAB Prospective Complications Study (PCS)
Sabita S. Soedamah-Muthu, Nish Chaturvedi, Daniel R. Witte, Lynda K. Stevens, Massimo Porta, John H. Fuller for the EURODIAB Prospective Complications Study Group

Burden and Rates of Treatment and Control of Cardiovascular Disease Risk Factors in Obesity: The Framingham Heart Study
Esther A. Molenaar, Shih-Jen Hwang, Ramachandran S. Vasan, Diederick E. Grobbee, James B. Meigs, Ralph B. D'Agostino, Sr., Daniel Levy, and Caroline S. Fox

Periodontal Disease and Incident Type 2 Diabetes: Results from the First National Health and Nutrition Examination Survey and its Epidemiologic Follow-Up Study
Ryan T. Demmer, David R. Jacobs, Jr., and Moïse Desvarieux

Differences in the Pattern of Antibiotic Prescription Profile and Recurrence Rate for Possible Urinary Tract Infections in Women With and Without Diabetes
Caroline Schneeberger, Ronald P. Stolk, J. Hans DeVries, Peter M. Schneeberger, Ron M. Herings, and Suzanne E. Geerlings

Inflammation Among Women With a History of Gestational Diabetes Mellitus and Diagnosed Diabetes in the Third National Health and Nutrition Examination Survey
Catherine Kim, Yiling J. Cheng, and Gloria L. Beckles

Sex Disparities in the Treatment and Control of Cardiovascular Risk Factors in Type 2 Diabetes
Ioanna Gouni-Berthold, Heiner K. Berthold, Christos S. Mantzoros, Michael Böhm, and Wilhelm Krone

Pathophysiology/Complications

Trends in High-Risk HLA Susceptibility Genes Among Colorado Youth With Type 1 Diabetes
Kendra Vehik, Richard F. Hamman, Dennis Lezotte, Jill M. Norris, Georgeanna J. Klingensmith, Marian Rewers, and Dana Dabelea

Adipose Tissue Lipolysis Is Upregulated in Lean and Obese Men During Acute Resistance Exercise
Athanasios Chatzinikolaou, Ioannis Fatouros, Anatoli Petridou, Athanasios Jamurtas, Alexandra Avloniti, Ioannis Douroudos, George Mastorakos, Christina Lazaropoulou, Ioannis Papassotiriou, Symeon Tournis, Asimina Mitrakou, and Vassilis Mougios

Increased Shear Rate Resistance and Fastest Kinetics of Erythrocyte Aggregation in Diabetes Measured With Ultrasound
Guy Cloutier, Audrey Zimmer, François T.H. Yu, and Jean-Louis Chiasson

Too Much Glucagon, Too Little Insulin: Time course of pancreatic islet dysfunction in new-onset type 1 diabetes
Rebecca J. Brown, Ninet Sinaii, and Kristina I. Rother

Cardiovascular and Metabolic Risk

Global Coronary Heart Disease Risk Assessment of Individuals With the Metabolic Syndrome in the U.S.
Khiet C. Hoang, Heli Ghandehari, Victor A. Lopez, Michael G. Barboza, and Nathan D. Wong

Adipokines and Incident Type 2 Diabetes in an Aboriginal Canadian Population: The Sandy Lake Health and Diabetes Project
Sylvia H. Ley, Stewart B. Harris, Philip W. Connelly, Mary Mamakeesick, Joel Gittelsohn, Robert A. Hegele, Ravi Retnakaran, Bernard Zinman, and Anthony J.G. Hanley

Sex Differences in Diabetes Risk and the Effect of Intensive Lifestyle Modification in the Diabetes Prevention Program
Leigh Perreault, Yong Ma, Sam Dagogo-Jack, Edward Horton, David Marrero, Jill Crandall, Elizabeth Barrett-Connor for the Diabetes Prevention Program

Association of Intrauterine Exposure to Maternal Diabetes and Obesity With Type 2 Diabetes in Youth: The SEARCH Case-Control Study
Dana Dabelea, Elizabeth J. Mayer-Davis, Archana P. Lamichhane, Ralph B. D'Agostino, Jr., Angela D. Liese, Kendra S. Vehik, K.M. Venkat Narayan, Phillip Zeitler, and Richard F. Hamman

Retinol-Binding Protein 4 and Insulin Resistance in Polycystic Ovary Syndrome
Samantha K. Hutchison, Cheryce Harrison, Nigel Stepto, Caroline Meyer, and Helena J. Teede

Insulin Resistance and Hyperinsulinemia: You can't have one without the other
Sun H. Kim and Gerald M. Reaven

Tumor Necrosis Factor- Antagonism Improves Vasodilation During Hyperinsulinemia in Metabolic Syndrome
Manfredi Tesauro, Francesca Schinzari, Valentina Rovella, Domenico Melina, Nadia Mores, Angela Barini, Marco Mettimano, Davide Lauro, Micaela Iantorno, Michael J. Quon, and Carmine Cardillo

Assessment of Aortic Pulse Wave Velocity and Cardiac Diastolic Function in Subjects With and Without the Metabolic Syndrome: HDL cholesterol is independently associated with cardiovascular function
Stijntje D. Roes, Reza Alizadeh Dehnavi, Jos J.M. Westenberg, Hildo J. Lamb, Bart J.A. Mertens, Jouke T. Tamsma, and Albert de Roos

Hyperinsulinemia in African-American Adolescents Compared With Their American White Peers Despite Similar Insulin Sensitivity: A reflection of upregulated β-cell function?
Tamara S. Hannon, Fida Bacha, Yan Lin, and Silva A. Arslanian

Reviews/Commentaries/ADA Statements

Meta-Analysis

Efficacy, Safety, and Tolerability of Pregabalin Treatment for Painful Diabetic Peripheral Neuropathy: Findings from seven randomized, controlled trials across a range of doses
Roy Freeman, Edith Durso-DeCruz, and Birol Emir

Rosiglitazone and Risk of Cancer: A meta-analysis of randomized clinical trials
Matteo Monami, Caterina Lamanna, Niccolò Marchionni, and Edoardo Mannucci Diabetes Care 2008 31: 1455-1460.

Perspectives on the News

Approaches to Treatment of Pre-Diabetes and Obesity and Promising New Approaches to Type 2 Diabetes
Zachary T. Bloomgarden

Editorials

Death to Carbohydrate Counting?
Nichola J. Davis and Judith Wylie-Rosett

Diabetes

Vol. 57 ; part 7

Perspectives in Diabetes:

Immunomodulation by Mesenchymal Stem Cells: A Potential Therapeutic Strategy for Type 1 Diabetes
Reza Abdi, Paolo Fiorina, Chaker N. Adra, Mark Atkinson, and Mohamed H. Sayegh

Neurophysiological Pathways to Obesity: Below Awareness and Beyond Individual Control
Deborah A. Cohen

Protein Kinase C Function in Muscle, Liver, and β-Cells and Its Therapeutic Implications for Type 2 Diabetes
Carsten Schmitz-Peiffer and Trevor J. Biden

Commentaries:

The Pol-e-Pill Finally Arrives
James A. Levine and Ronald M. Davis

Obesity: Increasing Awareness of Novel Environmental Factors
Kevin D. Niswender and Bettina M. Beech

Low-Affinity Major Histocompatibility Complex–Binding Peptides in Type 1 Diabetes
Eddie A. James and William W. Kwok

New Methodologies and Databases

Glucose Metabolism In Vivo in Four Commonly Used Inbred Mouse Strains
Eric D. Berglund, Candice Y. Li, Greg Poffenberger, Julio E. Ayala, Patrick T. Fueger, Shannon E. Willis, Marybeth M. Jewell, Alvin C. Powers, and David H. Wasserman

Metabolism

Plasma C5 Glucose–to–2H2O Ratio Does Not Provide an Accurate Assessment of Gluconeogenesis During Hyperinsulinemic-Euglycemic Clamps in Either Nondiabetic or Diabetic Humans
Rita Basu, Visvanathan Chandramouli, Betty Dicke, Bernard R. Landau, and Robert A. Rizza

Signal Transduction

Human Adenovirus Type 36 Enhances Glucose Uptake in Diabetic and Nondiabetic Human Skeletal Muscle Cells Independent of Insulin Signaling
Zhong Q. Wang, William T. Cefalu, Xian H. Zhang, Yongmei Yu, Jianhua Qin, Leslie Son, Pamela M. Rogers, Nazar Mashtalir, Justin R. Bordelon, Jianping Ye, and Nikhil V. Dhurandhar

Activation of Estrogen Receptor Is Crucial for Resveratrol-Stimulating Muscular Glucose Uptake via Both Insulin-Dependent and -Independent Pathways
Jen-Ying Deng, Po-Shiuan Hsieh, Jiung-Pang Huang, Long-Sheng Lu, and Li-Man Hung

Obesity Studies

Adiponectin Reduces Plasma Triglyceride by Increasing VLDL Triglyceride Catabolism
Liping Qiao, Chenhui Zou, Deneys R. van der Westhuyzen, and Jianhua Shao

Hormone-Sensitive Lipase Serine Phosphorylation and Glycerol Exchange Across Skeletal Muscle in Lean and Obese Subjects: Effect of β-Adrenergic Stimulation
Johan W.E. Jocken, Carsten Roepstorff, Gijs H. Goossens, Paula van der Baan, Marleen van Baak, Wim H.M. Saris, Bente Kiens, and Ellen E. Blaak

Blockade of 4 Integrin Signaling Ameliorates the Metabolic Consequences of High-Fat Diet–Induced Obesity
Chloé C. Féral, Jaap G. Neels, Christiane Kummer, Marina Slepak, Jerrold M. Olefsky, and Mark H. Ginsberg

Immunology and Transplantation

Weak Proinsulin Peptide–Major Histocompatibility Complexes Are Targeted in Autoimmune Diabetes in Mice
Matteo G. Levisetti, Danna M. Lewis, Anish Suri, and Emil R. Unanue

Protective Role of Programmed Death 1 Ligand 1 (PD-L1)in Nonobese Diabetic Mice: The Paradox in Transgenic Models
Chia-Jen Wang, Feng-Cheng Chou, Chi-Hong Chu, Jen-Chine Wu, Shih-Hua Lin, Deh-Ming Chang, and Huey-Kang Sytwu

Improved Vascular Engraftment and Graft Function After Inhibition of the Angiostatic Factor Thrombospondin-1 in Mouse Pancreatic Islets
Johan Olerud, Magnus Johansson, Jack Lawler, Nils Welsh, and Per-Ola Carlsson

Immunoglobulin-Like Transcript 3-Fc Suppresses T-Cell Responses to Allogeneic Human Islet Transplants in hu-NOD/SCID Mice
George Vlad, Vivette D. D'Agati, Qing-Yin Zhang, Zhuoru Liu, Eric K. Ho, Thalachallour Mohanakumar, Mark A. Hardy, Raffaello Cortesini, and Nicole Suciu-Foca

Islet Studies

Fructose-1,6-Bisphosphatase Overexpression in Pancreatic β-Cells Results in Reduced Insulin Secretion: A New Mechanism for Fat-Induced Impairment of β-Cell Function
Melkam Kebede, Jenny Favaloro, Jenny E. Gunton, D. Ross Laybutt, Margaret Shaw, Nicole Wong, Barbara C. Fam, Kathryn Aston-Mourney, Christian Rantzau, Anthony Zulli, Joseph Proietto, and Sofianos Andrikopoulos

MAPK Kinase Kinase-1 Is Essential for Cytokine-Induced c-Jun NH2-Terminal Kinase and Nuclear Factor-B Activation in Human Pancreatic Islet Cells
Dariush Mokhtari, Jason W. Myers, and Nils Welsh

Pathophysiology

Effect of Oral Amino Acids on Counterregulatory Responses and Cognitive Function During Insulin-Induced Hypoglycemia in Nondiabetic and Type 1 Diabetic People
Paolo Rossetti, Francesca Porcellati, Natalia Busciantella Ricci, Paola Candeloro, Patrizia Cioli, K. Sreekumaran Nair, Fausto Santeusanio, Geremia B. Bolli, and Carmine G. Fanelli

Circulating Retinol-Binding Protein-4 Concentration Might Reflect Insulin Resistance–Associated Iron Overload
José Manuel Fernández-Real, José María Moreno, and Wifredo Ricart

Protein Engineering Strategies for Sustained Glucagon-Like Peptide-1 Receptor–Dependent Control of Glucose Homeostasis
Kristen M. Picha, Mark R. Cunningham, Daniel J. Drucker, Ashok Mathur, Tatiana Ort, Michael Scully, Avery Soderman, Tracy Spinka-Doms, Vedrana Stojanovic-Susulic, Beth Ann Thomas, and Karyn T. O'Neil

Novel De Novo Mutation in Sulfonylurea Receptor 1 Presenting as Hyperinsulinism in Infancy Followed by Overt Diabetes in Early Adolescence
Maha Abdulhadi-Atwan, Jeremy D. Bushman, Sharona Tornovsky-Babaey, Avital Perry, Abdulsalam Abu-Libdeh, Benjamin Glaser, Show-Ling Shyng, and David H. Zangen

Complications

RAGE and Modulation of Ischemic Injury in the Diabetic Myocardium
Loredana G. Bucciarelli, Radha Ananthakrishnan, Yuying C. Hwang, Michiyo Kaneko, Fei Song, David R. Sell, Christopher Strauch, Vincent M. Monnier, Shi Fang Yan, Ann Marie Schmidt, and Ravichandran Ramasamy

Hyperglycemia-Induced Reactive Oxygen Species Toxicity to Endothelial Cells Is Dependent on Paracrine Mediators
Julia V. Busik, Susanne Mohr, and Maria B. Grant

Serum Heat Shock Protein 27 and Diabetes Complications in the EURODIAB Prospective Complications Study: A Novel Circulating Marker for Diabetic Neuropathy
Gabriella Gruden, Graziella Bruno, Nish Chaturvedi, Davina Burt, Casper Schalkwijk, Silvia Pinach, Coen D. Stehouwer, Daniel R. Witte, John H. Fuller, Paolo Cavallo Perin, and the EURODIAB Prospective Complications Study Group

Genetics

Haplotype Structure of the ENPP1 Gene and Nominal Association of the K121Q Missense Single Nucleotide Polymorphism With Glycemic Traits in the Framingham Heart Study
Elliot S. Stolerman, Alisa K. Manning, Jarred B. McAteer, Josée Dupuis, Caroline S. Fox, L. Adrienne Cupples, James B. Meigs, and Jose C. Florez

Diabetes Susceptibility in the Canadian Oji-Cree Population Is Moderated by Abnormal mRNA Processing of HNF1A G319S Transcripts
Lorna W. Harries, Melissa J. Sloman, Elizabeth A.C. Sellers, Andrew T. Hattersley, and Sian Ellard

Association Analysis of Type 2 Diabetes Loci in Type 1 Diabetes
Hui-Qi Qu, Struan F.A. Grant, Jonathan P. Bradfield, Cecilia Kim, Edward Frackelton, Hakon Hakonarson, and Constantin Polychronakos

Association of FTO With Obesity-Related Traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort
Amanda F. Marvelle, Leslie A. Lange, Li Qin, Linda S. Adair, and Karen L. Mohlke

Evaluation of the Association of IGF2BP2 Variants With Type 2 Diabetes in French Caucasians
Konsta Duesing, Ghazaleh Fatemifar, Guillaume Charpentier, Michel Marre, Jean Tichet, Serge Hercberg, Beverley Balkau, Philippe Froguel, and Fernando Gibson

Diabetic Medicine

Guest Editorial

Estimated average glucose (eAG): fit for purpose?
Eric S. Kilpatrick

Commentary from Copenhagen on the NICE guideline on management of diabetes and its complications from pre-conception to the postnatal period.Elisabeth R Mathiesen and Peter Damm

Letter

Methodology problems in using eGFR to investigate the prevalence of Renal Anaemia

Postprandial triglyceridaemia in men with impaired fasting glucose, impaired glucose tolerance and diabetes.
R. Oka, K. Yagi, S. Hifumi, S. Miyamoto, H. Mabuchi, M. Yamagishi, Y. Takeda, A. Inazu, A. Nohara, M. Kawashiri and J. Kobayashi

Original articles
Treatment of chronic diabetic foot ulcers with bemiparin: A randomised, triple-blind, placebo controlled, clinical trial M. Rullan, L. Cerdà, G. Frontera, L. Masmiquel and J. Llobera

Care Delivery

Glycaemic control and diabetes care utilization in young adults with Type 1 diabetes
Carina Sparud-Lundin, Ingbritt Öhrn, Ella Danielson Gun Forsander

A Comparison of Diabetes Clinics with Different Emphasis on Routine Care, Complications Assessment and Shared Care
NW Cheung DK Yue MA Kotowicz PA Jones and JR Flack

Treatment

Safety and Efficacy of Glargine compared with NPH Insulin for the Treatment of Type 2 Diabetes: A Meta-analysis of Randomized Controlled Trials
Lydia A. Bazzano, MD, PhD, Lauren J. Lee, PharmD, MS, Lizheng Shi, MsPharm, PhD, Kristi Reynolds, PhD, Jeffrey A. Jackson, MD and Vivian Fonseca, MD
Metabolism

Longitudinal Screening of Serum Lipids in Children and Adolescents with Type 1 Diabetes in a UK Clinic Population
Julie A Edge Tim James Brian Shine

Point-of-care testing as a tool for screening for diabetes and prediabetes.
Elaine Rush, Nic Crook and David Simmons

Variability of lipids in patients with type 2 diabetes taking statin treatment: implications for target setting.
Thozhukat Sathyapalan, Stephen L. Atkin, Eric S. Kilpatrick,

Effects of Fat Supplementation on Glycaemic Response and Gastric Emptying in Adolescents with Type 1 Diabetes
M Lodefalk, J Åman and P Bang

Metabolism
Childhood Body Mass Index (BMI), breastfeeding and risk of type 1 diabetes: findings from a longitudinal national birth cohort
Russell M Viner Peter C Hindmarsh Brent Taylor and Timothy J Cole

Combined association of maternal and paternal family history of diabetes on plasma leptin and adiponectin in overweight Hispanic children
Koebnick C, Kelly LA, Lane CJ, Roberts CK, Shaibi GQ, Toledo-Corral CM, Davis JN, Weigensberg MJ and Goran MI

Short reports

HbA1c: the case for using estimated average glucose (eAG)
Philip Home

Hypertriglyceridaemia is associated with an increased likelihood of albuminuria in extreme duration (> 50 years) Type 1 diabetes Manuscript DME-2008-00150C Daousi, SC Bain, AH Barnett and GV Gill

Plasma triglycerides and LDL-cholesterol are related in a parabolic fashion in the general population and patients with type 2 diabetes mellitus: long-term follow-up results from the Hoorn study
M.C.G.J. Brouwers, J.M. Dekker, M.M.J. van Greevenbroek, C.J.H. van der Kallen, R.J. Heine, T.W.A. de Bruin and C.D.A. Stehouwer

Review

NICE guidance on Diabetes in pregnancy: management of diabetes and its complications from pre-conception to the postnatal period. NICE clinical guideline 63. London, March 2008.

Case Report

Renal Failure and Rhabdomyolysis Associated With Sitagliptin and Simvastatin Use
David P. Kao, Holbrook E Kohrt, John Kugler

Psychological aspects

A LONGITUDINAL STUDY OF AFFECTIVE AND ANXIETY DISORDERS, DEPRESSIVE AFFECT AND DIABETES DISTRESS in ADULTS WITH TYPE 2 DIABETES
Lawrence Fisher, Marilyn M. Skaff, Joseph T. Mullan, Patricia Arean, Russell Glasgow and Umesh Masharani

PREVALENCE AND REASONS FOR INSULIN REFUSAL in BANGLADESHI PATIENTS WITH POORLY CONTROLLED TYPE 2 DIABETES IN EAST LONDON
Hamida Khan, Shawarna S Lasker, Tahseen A Chowdhury
Psychological aspects

Symptoms of Depression Prospectively Predict Poorer Self-Care in Patients with Type 2 Diabetes
JS Gonzalez, SA Safren, LM Delahanty, E Cagliero, DJ Wexler, JB Meigs and RW Grant

The personal cost of diabetic foot disease in developing world a study from Pakistan.
Syed Mansoor Ali, Aslam Fareed, Syed Mujahid Humail, Abdul Basit, Muhammad Yakoob Ahmedani, Asher Fawwad, M. Phil and Zahid Miyan.
Treatment

Diabetes, Obesity and Metabolism

Review Articles

Current treatment of non-alcoholic fatty liver disease
Mohamed H. Ahmed Christopher D. Byrne

Literature Reviews

Risk factor assessment for new onset diabetes: literature review
George Bakris,Jack Stockert, Mark Molitch, Qian Zhou, Annette Champion, Peter Bacher James Sowers, on behalf of the STAR Investigators

Original Articles

Glimepiride upregulates eNOS activity and inhibits cytokine-induced NF-B activation through a phosphoinoside 3-kinaseAkt-dependent pathwayT. Jojima, K. Suzuki, N. Hirama, K. Uchida Y. Hattori

Excess glycaemic excursions after an oral glucose tolerance test compared with a mixed meal challenge and self-measured home glucose profiles: is the OGTT a valid predictor of postprandial hyperglycaemia and vice versa?
J. J. Meier, B. Baller, B. A. Menge, B. Gallwitz, W. E. Schmidt M. A. Nauck

Treatment of Zucker diabetic fatty rats with AVE7688 improves vascular and neural dysfunction
C. L. Oltman, E. P. Davidson, L. J. Coppey, T. L. Kleinschmidt M. A. Yorek

Comparison of carvedilol and metoprolol on serum lipid concentration in diabetic hypertensive patients
D. S. H. Bell, G. L. Bakris J. B. McGill

Diabetes, Obesity and Metabolism

Volume 10, Issue 7, July 2008

Review Articles

Sudden cardiac death: influence of diabetes
P. M. Spooner
pages 523–532

Cardiovascular drugs as antidiabetic agents: evidence for the prevention of type 2 diabetes
D. P. Macfarlane, K. R. Paterson M. Fisher
pages 533–544


Original Articles

Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency
J. C. N. Chan, R. Scott, J. C. Arjona Ferreira, D. Sheng, E. Gonzalez, M. J. Davies, P. P. Stein, K. D. Kaufman, J. M. Amatruda D. Williams-Herman
pages 545–555

Overnight CSII as supplement to oral antidiabetic drugs in Type 2 diabetes
T. Parkner, M. K. Møller, J. W. Chen, T. Laursen, C. Jørgensen, J. S. Smedegaard, T. Lauritzen J. S. Christiansen
pages 556–563

Pioglitazone attenuates fatty acidinduced oxidative stress and apoptosis in pancreatic -cells
Y. Saitoh, C. Chun-ping, K. Noma, H. Ueno, M. Mizuta M. Nakazato
pages 564–573

Salacia oblonga root decreases cardiac hypertrophy in Zucker diabetic fatty rats: inhibition of cardiac expression of angiotensin II type 1 receptor
T. H. Huang, L. He, Q. Qin, Q. Yang, G. Peng, M. Harada, Y. Qi, J. Yamahara, B. D. Roufogalis Y. Li
pages 574–585

Improved metabolic control by Ipomoea batatas (Caiapo) is associated with increased adiponectin and decreased fibrinogen levels in type 2 diabetic subjects
B. Ludvik, M. Hanefeld, G. Pacini
pages 586–592

Research Letters

Patient-reported rating of gastrointestinal adverse effects during treatment of type 2 diabetes with the once-daily human GLP-1 analogue, liraglutide
M. Horowitz, T. Vilsbøll, M. Zdravkovic, M. Hammer, S. Madsbad
pages 593–596

Glimepiride as insulin sensitizer: increased liver and muscle responses to insulin
R. C. T. Mori, S. M. Hirabara, A. E. Hirata, M. M. Okamoto U. F. Machado
pages 596–600

Plasma visfatin is reduced after aerobic exercise in early onset type 2 diabetes mellitus
I. Brema, M. Hatunic, F. Finucane, N. Burns, J. J. Nolan, D. Haider, M. Wolzt, B. Ludvik
pages 600–602

New England Journal Of Medicine

12th June 2008

Effects of Intensive Glucose Lowering in Type 2 Diabetes
The ACCORD Study Group

Intensive Blood Glucose Control and Vascular Outcomes in Patients
with Type 2 Diabetes

The ADVANCE Collaborative Group

Diabetes, Obesity and Metabolism

Volume 10, Issue s2, July 2008


Review Articles
Optimum management of type 2 diabetes timely introduction, optimization and intensification of basal insulin
G. Dailey
pages 5–13

Reaching glycaemic targets while minimizing hypoglycaemia in insulin-treated type 2 diabetes patients
C. Mathieu S. Robbrecht
pages 14–23

Insulin glargine in type 2 diabetes in everyday clinical practice: 7 years experience
S. A. Schreiber
pages 24–34

Insulin therapy in elderly patients with type 2 diabetes: the role of insulin glargine
H. U. Janka
pages 35–41

Insulin management in overweight or obese type 2 diabetes patients: the role of insulin glargine
M. Davies K. Khunti
pages 42–49

Improving treatment satisfaction and other patient-reported outcomes in people with type 2 diabetes: the role of once-daily insulin glargine
C. Bradley C. J. B. Gilbride
pages 50–65

The cost-effectiveness of insulin glargine vs. neutral protamine Hagedorn insulin in type 2 diabetes: a focus on health economics
P. Levin
pages 66–75

Options for the intensification of insulin therapy when basal insulin is not enough in type 2 diabetes mellitus
D. Raccah
pages 76–82

Beyond insulin replacement: addressing the additional needs of the diabetes patient
G. Dailey
pages 83–97

The publication of this supplement has been supported by an unrestricted educational grant from sanofi-aventis.

Journal of Clinical Nursing

Volume 17:7b (July 2008)

The impact of type 1 diabetes and eating disorders: the perspective of individuals
Sharon Hillege, Barbara Beale, and Rose McMaster
pages 169–176

Autonomy through identification: a qualitative study of the process of identification used by people with type 2 diabetes
Albine Moser, Harry van der Bruggen, Cor Spreeuwenberg and Guy Widdershovenpages
pages 209–216

Diabetes Technology and Therapeutics

VOL 10 ; PART 3.

WellDoc Mobile Diabetes Management Randomized Controlled Trial : Change in Clinical and Behavioral Outcomes and Patient and Physician Satisfaction
Quinn , C . C . ; Clough , S . S . ; Minor , J . M . ; Lender , D . ; Okafor , M . C . ; Gruber - Baldini , A .
pp. 160-168.

Diabetes, Obesity and Metabolism

Original Articles

The relationship of glycaemic control and triglycerides in patients with diabetes mellitus: a PreCIS Database Study
M. B. Davidson, T. Hu, Guven Sain, B. Hoar, C. Stevenson B. J. Hoogwerf

Review Articles
Combination statinfibrate therapy: safety aspects
R. Franssen, M. Vergeer, E. S. G. Stroes J. J. P. Kastelein

Original Articles
Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency
J. C. N. Chan, R. Scott, J. C. Arjona Ferreira, D. Sheng, E. Gonzalez, M. J. Davies, P. P. Stein, K. D. Kaufman, J. M. Amatruda D. Williams-Herman

Family history of diabetes impacts on interactions between minimal model estimates of insulin sensitivity and glucose effectiveness
X. Lopez, C. Bouché, E. Tatro A. B. Goldfine

Monday, 30 June 2008

Diabetic Medicine

9th June 2008

Letter to the Editor

Short report

Investigation of Adducin 2 (beta) DNA polymorphisms in genetic predisposition to diabetic nephropathy in type 1 diabetes
D. Currie, A. P. Maxwell, D. Sadlier and A. J. McKnight and The Warren 3/ U. K. GoKin. D. Study Group

Review

RD Lawrence lecture Targeting GLP-1 release as a potential strategy for the therapy of type 2 diabetes
FM Gribble

Educational interventions for migrant South Asians with type 2 diabetes: a systematic review K Khunti, J Camosso-Stefinovic, M Carey, MJ Davies and MA Stone

Original articles

A 10-Year (1996-2005) prospective study of the incidence of type 1 diabetes in Moscow in the age-group 0-14 Years
E.A. Pronina, E.E. Petraikina, M.B. Antsiferov, O.V. Duchareva, A. Petrone, R. Buzzetti and P. Pozzilli

The Pro12Ala polymorphism of the PPARG gene is not associated with the metabolic syndrome in an urban population of middle aged Swedish Individuals.
Martina Montagnana, Cristiano Fava, Peter M Nilsson, Gunnar Engström, Bo Hedblad, Giuseppe Lippi, Pietro Minuz, Göran Berglund, Olle Melander

Foot Infections in Diabetes (DFIs) in the Outpatient Setting: an Italian Multicentre Observational Survey
Silvano Esposito, Sebastiano Leone, Silvana Noviello, Marco Fiore, Filomena Ianniello, Francesca Maria Felaco, Fabio Romagnoli, Ennio Sarli

Leptin - a predictor of abnormal glucose tolerance and prognosis in patients with myocardial infarction and without previously known type 2 diabetes
M. Wallander, S. Söderberg and A. Norhammar

New England Journal of Medicine

12th June 2008

Editorial

Intensive Glycemic Control in the ACCORD and ADVANCE Trials R.G. Dluhy and G.T. McMahon

Original Articles

Effects of Intensive Glucose Lowering in Type 2 Diabetes
The ACCORD Study Group


Intensive Blood Glucose Control and Vascular Outcomes
in Patients with Type 2 Diabetes
The ADVANCE Collaborative Group


Glycemic Targets and Cardiovascular Disease

Perspective

Redefining Quality -- Implications of Recent Clinical Trials

BMJ

7th June 2008

Letters

Screen women with gestational diabetes for type 2 diabetes
Mark Sillender
Self monitoring of blood glucose: the cost to patients
Monika M Safford and Louise B Russell
Why patients who self monitor glucose might be more depressed
Lucy M Candib

Practice

Management of type 2 diabetes: summary of updated NICE guidance
Philip Home, Jonathan Mant, Jose Diaz, Claire Turner on behalf of the Guideline Development Group
Commentary: controversies in NICE guidance on management of type 2 diabetes
Stephen Atkin and Christopher Walton

BMJ

14th June 2008

Research

Adherence to Mediterranean diet and risk of developing diabetes: prospective cohort study
M Á Martínez-González, C de la Fuente-Arrillaga, J M Nunez-Cordoba, F J Basterra-Gortari, J J Beunza, Z Vazquez, S Benito, A Tortosa, and M Bes-Rastrollo
BMJ Jun 2008; 336: 1348 - 1351

NICE guidance

1st - 15th June 2008

Diabetes - type 2 (update)
Diabetes - type 2 (update)
Diabetes (type 2) - newer agents
Diabetes in pregnancy

Friday, 13 June 2008

New Library book

New in the Health Sciences Library - 2 copies of
Managing clinical problems in diabetes, edited by Trisha Dunning and Glenn Ward
Shelved at 616.462 DUN