Diabetes related articles in the "Big 4"

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[Seminar] Gestational diabetes: the need for a common ground
...Gestational diabetes mellitus is a substantial and growing health concern in many parts of the world. Certain populations are especially vulnerable to developing this condition because of genetic, social, and environmental factors. Gestational diabetes has serious, long-term consequences for both baby and mother, including a predisposition to ob...
from The Lancet - 11:08 AM (52 minutes ago)

[Articles] Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis
...with gestational diabetes are at increased risk of developing type 2 diabetes, but the risk and time of onset have not been fully quantified. We therefore did a comprehensive systematic review and meta-analysis to assess the strength of association between these conditions and the effect of factors that might modify the risk.
from The Lancet - 11:08 AM (52 minutes ago)

[Comment] Fenofibrate and risk of minor amputations in diabetes
...type 2 diabetes, which shows a large effect of treatment on the rate of minor amputations during the 5-year study. This new report adds important information that gives clues to mechanisms and grounds for possible changes to guidelines for clinical management. As a brief reminder, the FIELD trial was designed to measure the effects of fenofibrat...
from The Lancet - 11:08 AM (52 minutes ago)

[Comment] Type 2 diabetes in children and adolescents
...type 2 diabetes in children and adolescents. Although probably not truly epidemic in proportion, the incidence of cases in high-risk ethnic populations now approaches 50% of all new cases of diabetes diagnosed in US adolescents. This increased prevalence of paediatric type 2 diabetes suggests impending future morbidity from diabetic complication...
from The Lancet - 11:08 AM (52 minutes ago)

[Comment] Continuous glucose monitoring in type 1 diabetes mellitus
...type 1 diabetes. With this new tool, basal insulin replacement could be optimised and meal-related insulin requirements accurately defined. Alarms could alert patients to impending hypoglycaemia and bolus doses adjusted depending on the direction of change in glucose levels before the meal.
from The Lancet - 11:08 AM (52 minutes ago)

[Perspectives] Living with diabetes: care beyond choice and control
...diagnosed with diabetes. He is getting used to injecting himself with insulin and thinking about how much he eats. As she looks at this morning's laboratory results his doctor seems happy. Mr Zomer is doing okay. Time for the next step in his treatment. So she explains to Mr Zomer that if his blood sugar were more tightly regulated, if he lowere...
from The Lancet - 11:08 AM (52 minutes ago)

[Articles] Effect of fenofibrate on amputation events in people with type 2 diabetes mellitus (FIELD study): a prespecified analysis of a randomised controlled trial
...type 2 diabetes mellitus substantially impair their quality of life and impose high costs on health-care systems. Our aim was to assess the effect of fenofibrate on amputation events in a large cohort of patients with type 2 diabetes.
from The Lancet - 11:08 AM (52 minutes ago)

[Comment] Diabetes: finding “a clean well-lighted place”
Human beings are social by their nature. Chronic diseases are isolating and can make the patient feel separated from others. For patients with chronic conditions, some of the main sources of human connection are the clinic, hospital, doctor, and other health professionals. The more demanding and threatening the disease, the greater the potential ne...
from The Lancet - 11:08 AM (52 minutes ago)

[Editorial] Diabetes—a global threat
...dedicated to diabetes—one of the greatest contributors to the global burden of disease. This themed issue, published in advance of the American Diabetes Association's scientific sessions in New Orleans on June 5–9, focuses on some of the major causes and most devastating complications of diabetes.
from The Lancet - 11:08 AM (52 minutes ago)

[Comment] Diabetes technology—now and in the future
...for diabetes management, we would not remotely be where we are today in reducing the terrible burden of this disease. Although for decades effective technology has been available to manage diabetes, the pace with which new technology has been introduced has accelerated greatly in recent years, and we now have a wide panoply of drugs and devices....
from The Lancet - 11:08 AM (52 minutes ago)

[Articles] Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials
...type 2 diabetes mellitus is unclear. We undertook a meta-analysis of randomised controlled trials to determine whether intensive treatment is beneficial.
from The Lancet - 11:08 AM (52 minutes ago)

[Comment] Gestational diabetes mellitus: an opportunity of a lifetime
...Gestational diabetes mellitus is defined as carbohydrate intolerance of any degree that begins or is first recognised during pregnancy. It complicates about 4% of all pregnancies in the USA and 3–5% in the UK, although reported US prevalence rates vary between 1–14%—attributable to factors such as differences in diagnostic criteria used to defin...
from The Lancet - 11:08 AM (52 minutes ago)

[Department of Error] Department of Error
...diabetes mellitus, and cancer in the occupied Palestinian territory. Lancet 2009; 373: 1041—In this Series paper (March 21), the third column heading in table 1 (p 1043) should be “Syria20”. In the section on Cancer, the fourth sentence of paragraph 3 (p 1044), should read “In theory some features of Palestinian society, including a high total f...
from The Lancet - 11:08 AM (52 minutes ago)

[Seminar] Stress hyperglycaemia
...existing diabetes. So-called stress hyperglycaemia is usually defined as hyperglycaemia resolving spontaneously after dissipation of acute illness. The term generally refers to patients without known diabetes, although patients with diabetes might also develop stress hyperglycaemia—a fact overlooked in many studies comparing hospital inpatients ...
from The Lancet - 11:08 AM (52 minutes ago)

[Comment] Hyperglycaemia and coronary heart disease: the meta picture
...type 2 diabetes. They report significant 17% and 15% reductions in events of non-fatal myocardial infarction and coronary heart disease, respectively, with better control of blood sugar. Because none of these trials individually reported a significant reduction in primary endpoints for coronary heart disease, a reasonable question is whether the...
from The Lancet - 11:08 AM (52 minutes ago)

[Perspectives] Profile: Karen Lam Siu-ling: tackling diabetes in Hong Kong
...would say diabetes education in Hong Kong.” For a woman who has scaled the ramparts of Hong Kong's most conservative medical establishment to become head of the University of Hong Kong's Department of Medicine, researched the significance of adiponectin in Chinese people, identified therapeutic compounds in Chinese medications, and charted the r...
from The Lancet - 11:08 AM (52 minutes ago)

BOOK REVIEW: Insulin Resistance: Childhood Precursors and Adult Disease
...syndrome and diabetes. The editors weave together three topic areas: epidemiology, pathophysiology, and treatment. ...
from New England Journal of Medicine - May 13, 2009 10:43 PM

CORRECTION: Incorrect Data in Text and Table in: Low-Dose Aspirin for Primary Prevention of Atherosclerotic Events in Patients With Type 2 Diabetes: A Randomized Controlled Trial
from JAMA current issue - May 12, 2009 9:30 PM

Recent Diabetes articles in the "Big 4"

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BMJ - current paper copy in library, electronic access 3 months delay - NHS Athens
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JAMA - current electronic access - NHS Athens
NEJM - current paper copy in library, partial electronic access to recent articles - no password, full text electronic access - 3 months delay - NHS Athens


[Articles] Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance
...type 2 diabetes mellitus is a major concern for health providers. We therefore assessed whether voglibose, an α-glucosidase inhibitor, could prevent the development of type 2 diabetes in high-risk Japanese individuals with impaired glucose tolerance.
from The Lancet - 10:29 AM (3 hours ago)

[Viewpoint] Towards a new developmental synthesis: adaptive developmental plasticity and human disease
...with gestational diabetes or maternal obesity, leading to multigenerational cycles of disease. Intervention strategies need to take account of these complexities.
from The Lancet - 10:29 AM (3 hours ago)

[Comment] Voglibose for prevention of type 2 diabetes mellitus
...type 2 diabetes in different populations with impaired glucose tolerance in the USA, north Europe, China, and Japan. Not only were the results impressive at the end of the intensive intervention trials, but long-term follow-up studies also confirmed the effect of lifestyle interventions for the prevention of diabetes in individuals at high risk ...
from The Lancet - 10:29 AM (3 hours ago)

CORRESPONDENCE: Glucose Control and Vascular Complications in Type 2 Diabetes
...Veterans Affairs Diabetes Trial (VADT), Duckworth et al. (Jan. 8 issue)1 ...
from New England Journal of Medicine - May 6, 2009 (2 days ago)

[Obituary] Obituary: Mark H Beers
...complications of diabetes aged 54 years.
from The Lancet - May 1, 2009 10:03 AM

Diabetes articles in the "Big 4"

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[Comment] Prevention of diabetic retinopathy
...patients with diabetes develop retinopathy if they live long enough; 50% of patients with type 1 diabetes and 30% of those with type 2 diabetes can expect to develop sight-threatening retinopathy in their lifetime and need intervention to reduce the risk of vision loss. Good control of blood glucose and blood pressure greatly reduces this risk. ...
The Lancet - Apr 17, 2009 10:11 AM

REVIEW ARTICLE: Mechanisms of Disease: Genetics of Type 1A Diabetes
...type 1 diabetes have been studied for more than 30 years, but only recently, with modern genetic tools, has the importance of seemingly minor contributors been appreciated. This article reviews recent advances in knowledge of the genetics of type 1 diabetes and shows how this information could find clinical applications of considerable consequen...
New England Journal of Medicine - Apr 15, 2009 10:44 PM

CME: Genetics of Type 1A Diabetes
(No abstract is available for this citation)
New England Journal of Medicine - Apr 15, 2009 10:44 PM

COMMENTARY: Can Diabetes Be Cured?: Potential Biological and Mechanical Approaches
JAMA current issue - Apr 14, 2009 3:37 PM

JAMA PATIENT PAGE: Diabetes
JAMA current issue - Apr 14, 2009 3:37 PM

ORIGINAL CONTRIBUTION: Cardiac Outcomes After Screening for Asymptomatic Coronary Artery Disease in Patients With Type 2 Diabetes: The DIAD Study: A Randomized Controlled Trial
...type 2 diabetes. But the utility of screening patients with type 2 diabetes for asymptomatic CAD is controversial. Objective To assess whether routine screening for CAD identifies patients with type 2 diabetes as being at high cardiac risk and whether it affects their cardiac outcomes. Design, Setting, and Patients The Detection of Ischemia in...
JAMA current issue - Apr 14, 2009 3:37 PM

LETTERS: Low-Glycemic Index vs High-Cereal Fiber Diet in Type 2 Diabetes--Reply
JAMA current issue - Apr 14, 2009 3:37 PM

ORIGINAL CONTRIBUTION: C-Peptide Levels and Insulin Independence Following Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus
...type 1 diabetes mellitus (DM) were reported. Most patients became insulin free with normal levels of glycated hemoglobin A1c (HbA1c) during a mean 18.8-month follow-up. To investigate if this effect was due to preservation of beta-cell mass, continued monitoring was performed of C-peptide levels after stem cell transplantation in the 15 original...
JAMA current issue - Apr 14, 2009 3:37 PM

LETTERS: Birth Weight and Type 2 Diabetes in Adults
JAMA current issue - Apr 14, 2009 3:37 PM

ORIGINAL CONTRIBUTION: Hypoglycemic Episodes and Risk of Dementia in Older Patients With Type 2 Diabetes Mellitus
...type 1 diabetes, no studies to date have evaluated whether hypoglycemia is a risk factor for dementia in older patients with type 2 diabetes. Objective To determine if hypoglycemic episodes severe enough to require hospitalization are associated with an increased risk of dementia in a population of older patients with type 2 diabetes followed u...
JAMA current issue - Apr 14, 2009 3:37 PM

MEDICAL NEWS & PERSPECTIVES: FDA Warns Against Shared Insulin Pens
JAMA current issue - Apr 14, 2009 3:37 PM

SPECIAL COMMUNICATION: Human Pancreatic Islets and Diabetes Research
...options for diabetes patients and in attempting to prevent the development of this disease. The national Islet Cell Resource Center Consortium provides human pancreatic islets for diabetes research while simultaneously addressing the need to improve islet isolation and transplantation technologies. Since its inception in 2001, the consortium has...
JAMA current issue - Apr 14, 2009 3:37 PM

BOOK AND MEDIA REVIEWS: Controversies in Treating Diabetes: Clinical and Research Aspects
JAMA current issue - Apr 14, 2009 3:37 PM

COMMENTARY: Bariatric Surgery and Diabetes: Who Should Be Offered the Option of Remission?
JAMA current issue - Apr 14, 2009 3:37 PM

LETTERS: Long-term Mortality in Cancer Patients With Preexisting Diabetes
JAMA current issue - Apr 14, 2009 3:37 PM

MEDICAL NEWS & PERSPECTIVES: Hemoglobin A1c Poised to Become Preferred Test for Diagnosing Diabetes
JAMA current issue - Apr 14, 2009 3:37 PM

BOOK AND MEDIA REVIEWS: Management of Diabetes Mellitus: A Guide to the Pattern Approach
JAMA current issue - Apr 14, 2009 3:37 PM

BOOK AND MEDIA REVIEWS: Type 2 Diabetes Mellitus: An Evidence-Based Approach to Practical Management
JAMA current issue - Apr 14, 2009 3:37 PM

COMMENTARY: Glucose Control in Type 2 Diabetes: Still Worthwhile and Worth Pursuing
JAMA current issue - Apr 14, 2009 3:37 PM

LETTERS: Low-Glycemic Index vs High-Cereal Fiber Diet in Type 2 Diabetes
JAMA current issue - Apr 14, 2009 3:37 PM

MEDICAL NEWS & PERSPECTIVES: Artificial Pancreas May Soon Be a Reality
JAMA current issue - Apr 14, 2009 3:37 PM

THE WORLD IN MEDICINE: Diabetes Viral Trigger?
JAMA current issue - Apr 14, 2009 3:37 PM

BOOK AND MEDIA REVIEWS: The Discovery of Insulin: Twenty-fifth Anniversary Edition
JAMA current issue - Apr 14, 2009 3:37 PM

THE WORLD IN MEDICINE: Arrhythmia and Diabetes
JAMA current issue - Apr 14, 2009 3:37 PM

ORIGINAL CONTRIBUTION: Relationship Between Spontaneous and Iatrogenic Hypoglycemia and Mortality in Patients Hospitalized With Acute Myocardial Infarction
Context While glucose control is recommended by professional societies for patients with hyperglycemia hospitalized with acute myocardial infarction (AMI), enthusiasm for glucose lowering is tempered, in part, by concerns of inducing hypoglycemia. Yet, whether episodic hypoglycemia that occurs as a result of glucose-lowering therapy is harmful in ...
JAMA current issue - Apr 14, 2009 3:37 PM

LETTERS: Birth Weight and Type 2 Diabetes in Adults
JAMA current issue - Apr 14, 2009 3:37 PM

MEDICAL NEWS & PERSPECTIVES: Scientists See Hope, Peril in Trials of Islet Transplantation for Diabetes
JAMA current issue - Apr 14, 2009 3:37 PM

FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION: QuickStats: Age-Adjusted Death Rates* for Diabetes, by Race and Sex -- United States, 1979-2006{dagger}
JAMA current issue - Apr 14, 2009 3:37 PM

COMMENTARY: The Public Health Response to Diabetes--Two Steps Forward, One Step Back
JAMA current issue - Apr 14, 2009 3:37 PM

LETTERS: Birth Weight and Type 2 Diabetes in Adults--Reply
JAMA current issue - Apr 14, 2009 3:37 PM

EDITORIAL: Progress in Diabetes Research--What's Next
JAMA current issue - Apr 14, 2009 3:37 PM

JAMA 100 YEARS AGO: THE PANCREAS AND THE LIVER IN DIABETES
JAMA current issue - Apr 14, 2009 3:37 PM

LETTERS: Long-term Mortality in Cancer Patients With Preexisting Diabetes--Reply
JAMA current issue - Apr 14, 2009 3:37 PM

[Comment] PCI or CABG in coronary artery disease?
...patients with diabetes (hazard ratio 0·70, 95% CI 0·56–0·87) and in those aged 65 years or older (0·82, 0·70–0·97). Furthermore, the combined endpoint of death or repeat revascularisation was reduced with CABG (10%) compared with PCI (25%; 0·41, 0·37–0·45). Being probably the most definitive and authoritative analyses of the previous randomised ...
The Lancet - Apr 3, 2009 10:19 AM

[Comment] Speakable and unspeakable facts about BMI and mortality
...diabetes, and liver disease. These results conclude once and for all what has been observed in smaller studies: obesity shortens lifespan.
The Lancet - Mar 27, 2009 10:40 AM

CORRESPONDENCE: Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes
...type 2 diabetes among people at high risk ...
New England Journal of Medicine - Mar 25, 2009 9:45 PM

Diabetes related articles in the "Big 4"

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BMJ - current paper copy in library, electronic access 3 months delay - NHS Athens
Lancet - electronic access 2 months delay - NHS Athens
JAMA - current electronic access - NHS Athens
NEJM - current paper copy in library, partial electronic access to recent articles - no password, full text electronic access - 3 months delay - NHS Athens


[Comment] PCI or CABG in coronary artery disease?
...patients with diabetes (hazard ratio 0·70, 95% CI 0·56–0·87) and in those aged 65 years or older (0·82, 0·70–0·97). Furthermore, the combined endpoint of death or repeat revascularisation was reduced with CABG (10%) compared with PCI (25%; 0·41, 0·37–0·45). Being probably the most definitive and authoritative analyses of the previous randomised ...
The Lancet - Apr 3, 2009 (6 days ago)

[Comment] Speakable and unspeakable facts about BMI and mortality
...diabetes, and liver disease. These results conclude once and for all what has been observed in smaller studies: obesity shortens lifespan.
The Lancet - Mar 27, 2009 10:40 AM

CORRESPONDENCE: Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes
...type 2 diabetes among people at high risk ...
New England Journal of Medicine - Mar 25, 2009 9:45 PM


[Series] Cardiovascular diseases, diabetes mellitus, and cancer in the occupied Palestinian territory
...diabetes mellitus, tobacco smoking, and dyslipidaemia—are high and similar to those in neighbouring countries. The urbanisation and continuing nutritional change from a healthy Mediterranean diet to an increasingly western-style diet is associated with reduced activity, obesity, and a loss of the protective effect of the traditional diet. Rates ...
The Lancet - Mar 20, 2009 12:26 PM

Screening for type 2 diabetes in primary care
Peter E H Schwarz, Jiang Li, and Stefan R Bornstein
BMJ 2009;338 b973

Predicting risk of type 2 diabetes in England and Wales: prospective derivation and validation of QDScore
Julia Hippisley-Cox, Carol Coupland, John Robson, Aziz Sheikh, and Peter Brindle
BMJ 2009;338 b880
[NEWS] Number of global clinical trials done in UK fell by two thirds after EU directive
BMJ current issue - Mar 13, 2009 11:56 AM

Recent diabetes articles in the 'Big 4'

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[EDITORIALS] Tight control of blood glucose in long standing type 2 diabetes
BMJ current issue - Mar 6, 2009 1:04 AM

[Articles] Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention study Since insulin resistance is thought to be the underlying mechanism for metabolic syndrome, affected individuals might be sensitive to a dietary sodium intervention. We aimed to examine the association between metabolic syndrome and salt sensitivity of blood pressure. The Lancet - Mar 6, 2009 10:55 AM

[NEWS] New US health bill must include prevention measures, senator says
BMJ current issue - Mar 4, 2009 11:12 AM


IMAGES IN CLINICAL MEDICINE: Proliferative Diabetic Retinopathy
A 56-year-old man with diabetes presented with a several-month history of decreased vision in the left eye. There was no history of trauma, flashes of light, or floaters. Visual acuity ...
New England Journal of Medicine - Feb 25, 2009 11:26 PM

Diabetes related articles in the "Big 4"

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[ENDGAMES] An episode of transient neurological symptoms
BMJ current issue - Feb 26, 2009 (yesterday)

IMAGES IN CLINICAL MEDICINE: Proliferative Diabetic Retinopathy
...man with diabetes presented with a several-month history of decreased vision in the left eye. There was no history of trauma, flashes of light, or floaters. Visual acuity ...
New England Journal of Medicine - Feb 25, 2009 (2 days ago)

ORIGINAL CONTRIBUTION: Association Between Diabetes and Perinatal Depression Among Low-Income Mothers
...and diabetes complicates up to 9% of pregnancies. Prior research shows a higher rate of major depression among individuals with diabetes. Objective To examine the association between diabetes and depression during pregnancy and the postpartum period among a sample of low-income women. Design, Setting, and Patients Retrospective cohort study us...
JAMA current issue - Feb 24, 2009 (3 days ago)

[LETTERS] We need to address the issue of "mild troponinaemia"
BMJ current issue - Feb 24, 2009 (3 days ago)

[NEWS] Older Americans are not as healthy as older Europeans, study says
BMJ current issue - Feb 18, 2009 12:36 PM

LETTERS: Association of Bisphenol A With Diabetes and Other Abnormalities
JAMA current issue - Feb 17, 2009 9:33 PM

LETTERS: Association of Bisphenol A With Diabetes and Other Abnormalities
JAMA current issue - Feb 17, 2009 9:33 PM

LETTERS: Association of Bisphenol A With Diabetes and Other Abnormalities
JAMA current issue - Feb 17, 2009 9:33 PM

LETTERS: Association of Bisphenol A With Diabetes and Other Abnormalities--Reply
JAMA current issue - Feb 17, 2009 9:33 PM

[LETTERS] NICE guidance on insulin pumps is not without drawbacks
BMJ current issue - Feb 17, 2009 4:23 PM

Recent "Big 4" diabetes articles

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BMJ - current paper copy in library, electronic access 3 months delay - NHS Athens
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NEJM - current paper copy in library, partial electronic access to recent articles - no password, full text electronic access - 3 months delay - NHS Athens

[EDITORIALS] Late onset hypogonadism
BMJ current issue - 1:21 PM (1 hour ago)

[Correspondence] Response to “Rosiglitazone no longer recommended”
...the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
The Lancet - 11:12 AM (3 hours ago)

[EDITORIALS] Systemic management of diabetic retinopathy
BMJ current issue - Feb 12, 2009 (yesterday)

FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION: Self-Reported Prediabetes and Risk-Reduction Activities--United States, 2006
JAMA current issue - Feb 10, 2009 (3 days ago)

[NEWS] Asian-African summit explores how to tackle rise in non-communicable diseases
BMJ current issue - Feb 9, 2009 (4 days ago)

[Articles] Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial
...type 2 diabetes mellitus are needed to retain insulin–glucose coupling and lower the risk of weight gain and hypoglycaemia. We aimed to investigate the safety and efficacy of liraglutide as monotherapy for this disorder.
The Lancet - Feb 6, 2009 10:21 AM

[Comment] Treatment of type 2 diabetes with incretin-based therapies
...type 2 diabetes. GLP-1 is a gut-derived incretin hormone that stimulates insulin and suppresses glucagon secretion in a glucose-dependent manner, with the result that the ability of GLP-1 to produce hypoglycaemia is reduced (). GLP-1 slows gastric emptying, and long-term studies have shown that therapy with GLP-1 reduces appetite and food intake...
The Lancet - Feb 6, 2009 10:21 AM

CORRECTIONS: Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes
...Type 2 Diabetes . In Table 2, the footnote symbol next to the P Value column head should be ...
New England Journal of Medicine - Feb 4, 2009 10:57 PM

[NEWS] Westminster primary care trust introduces programme to prevent heart disease
BMJ current issue - Feb 3, 2009 11:27 AM

Latest diabetes news in the Big 4

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[NEWS] BMJ Group Awards--shortlisted candidates in nine categories
BMJ current issue - Jan 29, 2009 (19 hours ago)

BOOK REVIEW: Type 2 Diabetes Mellitus: An Evidence-Based Approach to Practical Management
...type 2 diabetes and its coexisting diseases among people of all ...
New England Journal of Medicine - Jan 28, 2009 (2 days ago)

[LETTERS] Cut caffeine in pregnancy?
BMJ current issue - Jan 28, 2009 (2 days ago)

[EDITORIALS] Heart failure with a normal ejection fraction
BMJ current issue - Jan 27, 2009 (3 days ago)

[CLINICAL REVIEW] HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity
BMJ current issue - Jan 26, 2009 (4 days ago)

[NEWS] Drug eluting stents remain a "major concern" in the longer term, finds study
BMJ current issue - Jan 22, 2009 12:02 PM

CORRESPONDENCE: Follow-up of Intensive Glucose Control in Type 2 Diabetes
...Kingdom Prospective Diabetes Study (UKPDS) reported by Holman et al. (Oct. 9 issue)1 shows the ...
New England Journal of Medicine - Jan 21, 2009 10:38 PM

[NEWS] Aid agencies face daunting humanitarian task in war ravaged Gaza
BMJ current issue - Jan 21, 2009 5:31 PM

[NEWS] Two thirds of US prisoners with chronic conditions in local jails do not get medical care, study shows
BMJ current issue - Jan 20, 2009 11:35 AM

[NEWS] Eli Lilly pays record $1.4bn for promoting off-label use of olanzapine
BMJ current issue - Jan 20, 2009 11:35 AM

[EDITORIALS] Antibiotic prophylaxis for minor dermatological surgery in primary care
BMJ current issue - Jan 15, 2009 12:09 PM

COMMENTARY: Transparency Standards for Diabetes Performance Measures
JAMA current issue - Jan 13, 2009 9:19 PM

COMMENTARY: Sliding Scale Insulin--Time to Stop Sliding
JAMA current issue - Jan 13, 2009 9:19 PM

[Case Report] The insulin ball
...type 1 diabetes, was admitted to our hospital, for investigation of apparent insulin resistance. Since January, 2004, he had been taking insulin in a longacting (glargine) and a shortacting (lispro) form, at a total of 66 units a day. Despite the dose being gradually increased to 94 units a day, his blood glucose concentrations had subsequently ...
The Lancet - Jan 9, 2009 10:18 AM

[Comment] International collaborative research on Charcot's disease
...Institute of Diabetes, Digestive and Kidney Diseases and the Office of Rare Diseases of the National Institutes of Health hosted an international symposium on Charcot's disease of the foot (neuroarthropathy) in diabetes, in Bethesda, MD, USA. The intention was to bring together experts from different countries with the aim of promoting internati...
The Lancet - Jan 9, 2009 10:18 AM

[Correspondence] Exenatide for type 2 diabetes
...type 2 diabetes (Oct 4, p 1240) is questionable. Drucker and colleagues found that the weekly treatment was superior to the twice daily regimen; however, the study was only designed to test non-inferiority, and no analysis of superiority, should the demonstration of non-inferiority be found, was apparently planned. As a consequence, we cannot ex...
The Lancet - Jan 9, 2009 10:18 AM

[Correspondence] Exenatide for type 2 diabetes – Authors' reply
Although not explicitly stated in our paper, the study was designed as a non-inferiority trial followed by a test of superiority if non-inferiority was concluded. Specifically, a two-sided 95% CI was used to compare the active treatment with the control. In such tests, if the upper limit of the CI falls below the prespecified non-inferiority margin...
The Lancet - Jan 9, 2009 10:18 AM

[FEATURE] Unravelling the secrets of ageing
BMJ current issue - Jan 8, 2009 5:17 PM

CME: Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes
(No abstract is available for this citation)
New England Journal of Medicine - Jan 7, 2009 10:39 PM

ORIGINAL ARTICLE: Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes
...type 2 diabetes were randomly assigned to receive either standard or intensive glucose control. Other cardiovascular risk factors were treated uniformly. The glycated hemoglobin goal was an absolute reduction of 1.5 percentage points in the intensive-therapy group. There was no significant difference between the two groups for the rates of major...
New England Journal of Medicine - Jan 7, 2009 10:39 PM

CORRESPONDENCE: Continuous Glucose Monitoring and Type 1 Diabetes
...The Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group (Oct. 2 issue)1 concluded that "continuous glucose ...
New England Journal of Medicine - Jan 7, 2009 10:39 PM

[RESEARCH] Comorbidity and repeat admission to hospital for adverse drug reactions in older adults: retrospective cohort study
...moderate diabetes (1.18, 1.07 to 1.30), diabetes with chronic complications (1.91, 1.65 to 2.22), renal disease (1.93, 1.71 to 2.17), any malignancy including lymphoma and leukaemia (1.87, 1.68 to 2.09), and metastatic solid tumours (2.25, 1.92 to 2.64) were strong predictive factors. Comorbidities requiring continuing care predicted a reduced l...
BMJ current issue - Jan 7, 2009 6:05 PM

[EDITORIALS] Readmissions as a result of adverse drug reactions in older people
BMJ current issue - Jan 7, 2009 6:05 PM

ORIGINAL CONTRIBUTION: Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)
...type 2 diabetes mellitus in the selenium group (relative risk, 1.07; 99% CI, 0.94-1.22; P = .16) but not in the selenium + vitamin E group. Conclusion Selenium or vitamin E, alone or in combination at the doses and formulations used, did not prevent prostate cancer in this population of relatively healthy men. Trial Registration clinicaltrials...
JAMA current issue - Jan 6, 2009 9:22 PM

[CLINICAL REVIEW] Evaluating cardiovascular risk assessment for asymptomatic people
BMJ current issue - Jan 5, 2009 12:31 PM

[PRACTICE] Diabetic ketoacidosis caused by exposure of insulin pump to heat and sunlight
BMJ current issue - Jan 5, 2009 12:31 PM

ORIGINAL ARTICLE: Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease
...Type 1 diabetes and celiac disease, both of which are associated with HLA class II genes, cosegregate in populations, suggesting a common genetic origin. In this article, the authors tested whether any non-HLA loci are shared. They report susceptibility alleles shared by both diseases, indicating that common biologic mechanisms underlie these im...
New England Journal of Medicine - Dec 24, 2008 10:47 PM

EDITORIAL: Shared Genetic Risk Factors for Type 1 Diabetes and Celiac Disease
Some families seem to be afflicted with more than their fair share of chronic illness -- and sometimes more than one. Why does a particular disease develop in some members ...
New England Journal of Medicine - Dec 24, 2008 10:47 PM

CORRESPONDENCE: Concordance for Islet Autoimmunity among Monozygotic Twins
...type 1 diabetes among the monozygotic twins of patients with type 1 diabetes is ...
New England Journal of Medicine - Dec 24, 2008 10:47 PM

FROM THE CENTERS FOR DISEASE CONTROL AND PREVENTION: State-Specific Incidence of Diabetes Among Adults--Participating States, 1995-1997 and 2005-2007
JAMA current issue - Dec 23, 2008 9:34 PM

ORIGINAL CONTRIBUTION: Short Sleep Duration and Incident Coronary Artery Calcification
...diabetes, inflammatory markers, alcohol consumption, depression, hostility, self-reported medical conditions) were measured at both baseline and follow-up. Sleep metrics (wrist actigraphy measured duration and fragmentation, daytime sleepiness, overall quality, self-reported duration) were examined for association with incident calcification. Pa...
JAMA current issue - Dec 23, 2008 9:34 PM

REVIEW: Birth Weight and Risk of Type 2 Diabetes: A Systematic Review
...type 2 diabetes. However, the strength, consistency, independence, and shape of the association have not been systematically examined. Objective To conduct a quantitative systematic review examining published evidence on the association of birth weight and type 2 diabetes in adults. Data Sources and Study Selection Relevant studies published b...
JAMA current issue - Dec 23, 2008 9:34 PM

EARLY RELEASE: Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes
...type 2 diabetes mellitus remain uncertain. Methods We randomly assigned 1791 military veterans (mean age, 60.4 ...
New England Journal of Medicine - Dec 17, 2008 11:18 PM

[RESEARCH METHODS & REPORTING] Evaluating service delivery interventions to enhance patient safety
BMJ current issue - Dec 17, 2008 11:41 AM

LETTERS: Arsenic Exposure and Diabetes Mellitus in the United States--Reply
JAMA current issue - Dec 16, 2008 9:54 PM

REVIEW: Long-term All-Cause Mortality in Cancer Patients With Preexisting Diabetes Mellitus: A Systematic Review and Meta-analysis
...Diabetes mellitus appears to be a risk factor for some cancers, but the effect of preexisting diabetes on all-cause mortality in newly diagnosed cancer patients is less clear. Objective To perform a systematic review and meta-analysis comparing overall survival in cancer patients with and without preexisting diabetes. Data Sources We searched ...
JAMA current issue - Dec 16, 2008 9:54 PM

ORIGINAL CONTRIBUTION: Effect of a Low-Glycemic Index or a High-Cereal Fiber Diet on Type 2 Diabetes: A Randomized Trial
...type 2 diabetes but debate over their effectiveness continues due to trial limitations. Objective To test the effects of low–glycemic index diets on glycemic control and cardiovascular risk factors in patients with type 2 diabetes. Design, Setting, and Participants A randomized, parallel study design at a Canadian university hospital research ...
JAMA current issue - Dec 16, 2008 9:54 PM

LETTERS: Arsenic Exposure and Diabetes Mellitus in the United States
JAMA current issue - Dec 16, 2008 9:54 PM

[ANALYSIS] New design rules for driving innovation in access to secondary care in the NHS
BMJ current issue - Dec 15, 2008 4:57 PM

[PRACTICE] Obesity and pregnancy
BMJ current issue - Dec 15, 2008 12:42 PM

[PRACTICE] Planning a patient's discharge from hospital
BMJ current issue - Dec 12, 2008 3:58 PM

[Correspondence] Renal outcomes in the ONTARGET study
...disease or diabetes and end-organ damage. Combination treatment had previously shown beneficial effects in the progression of diabetic and non-diabetic renal disease. Such studies, combined with the hypothesis that reducing proteinuria is the key to a better renal prognosis, prompted the extensive use of combination treatment among nephrologists...
The Lancet - Dec 12, 2008 10:44 AM

[EDITORIALS] Promotion of exercise in primary care
BMJ current issue - Dec 12, 2008 5:00 AM

[EDITORIALS] The health of nations
BMJ current issue - Dec 11, 2008 6:22 PM

EARLY RELEASE: Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease
...type 1 diabetes and celiac disease, cosegregate in populations, suggesting a common genetic origin. Since both diseases are associated with the HLA class II genes on ...
New England Journal of Medicine - Dec 10, 2008 10:40 PM

EARLY RELEASE: Shared Genetic Risk Factors for Type 1 Diabetes and Celiac Disease
(No abstract is available for this citation)
New England Journal of Medicine - Dec 10, 2008 10:40 PM

[EDITORIALS] Cardiovascular disease and cancer in very old age
BMJ current issue - Dec 10, 2008 1:14 PM

[NEWS] US company designs gun for people with arthritic hands
BMJ current issue - Dec 10, 2008 1:14 PM

ORIGINAL CONTRIBUTION: Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)
...type 2 diabetes mellitus in the selenium group (relative risk, 1.07; 99% CI, 0.94-1.22; P = .16) but not in the selenium + vitamin E group.Conclusion Selenium or vitamin E, alone or in combination at the doses and formulations used, did not prevent prostate cancer in this population of relatively healthy men.Trial Registration clinicaltrials.g...
JAMA current issue - Dec 9, 2008 9:29 PM