This week's Diabetes Bulletin...

...
Showing posts with label drug therapy. Show all posts
Showing posts with label drug therapy. Show all posts

Thursday, 4 December 2008

Scottish Medicines Consortium (SMC)

Scottish Medicines Consortium (SMC): http://www.scottishmedicines.org/

Accepted for use within NHS Scotland:
  • insulin lispro (Humalog KwikPen) for adults and children with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis
  • insulin lispro (Humalog Mix25, Mix50 KwikPen) for adults and children with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis

Friday, 7 November 2008

Recent diabetes related articles in the Big 4

Access
BMJ - current paper copy in library, electronic access 3 months delay - NHS Athens
Lancet - electronic access 2 months delay - NHS Athens
JAMA - current electronic access - NHS Athens
NEJM - current paper copy in library, partial electronic access to recent articles - no password, full text electronic access - 3 months delay - NHS Athens

[NEWS] Major US consumer group asks FDA to ban drug for diabetes
BMJ current issue - Nov 5, 2008 (2 days ago)

LAB REPORTS: Diabetes and Bacteria
JAMA current issue - Nov 4, 2008 (3 days ago)

LAB, FIELD, & CLINIC: Adult Pancreatic Cells "Reprogrammed" Into Rarer Insulin-Producing Cells
JAMA current issue - Nov 4, 2008 (3 days ago)

COMMENTARY: Glucose Lowering to Control Macrovascular Disease in Type 2 Diabetes: Treating the Wrong Surrogate End Point?
JAMA current issue - Nov 4, 2008 (3 days ago)

[RESEARCH] Prevention of type 2 diabetes in British Bangladeshis: qualitative study of community, religious, and professional perspectives
...relation to diabetes prevention in the Bangladeshi community. Design Qualitative study (focus groups and semistructured interviews). Setting Tower Hamlets, a socioeconomically deprived London borough, United Kingdom. Participants Bangladeshi people without diabetes (phase 1), religious leaders and Islamic scholars (phase 2), and health professio...
BMJ current issue - Nov 4, 2008 (3 days ago)

[EDITORIALS] Preventing diabetes in Bangladeshi people in Britain
BMJ current issue - Nov 4, 2008 (3 days ago)

[Editorial] Rosiglitazone no longer recommended
...two leading diabetes societies. For the first time, the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) have issued guidelines that explicitly advise against the use of GSK's rosiglitazone for type-2 diabetes.
The Lancet - Oct 31, 2008 11:13 AM

ORIGINAL ARTICLE: GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes
...type 1 diabetes mellitus, would reverse recent-onset disease. C-peptide levels declined in both the treatment group and the control group, without significant between-group differences at month 15 (the primary end point), but they had declined significantly more slowly with treatment by month 30. The authors conclude that alum-formulated GAD may...
New England Journal of Medicine - Oct 29, 2008 9:30 PM

EDITORIAL: Immunotherapy on Trial for New-Onset Type 1 Diabetes
...Type 1 diabetes mellitus is an autoimmune disease in which pathologic, autoreactive T cells of the immune system attack the insulin-secreting pancreatic islets of Langerhans. Cytotoxic T cells, which bear ...
New England Journal of Medicine - Oct 29, 2008 9:30 PM

[PRACTICE] Request for slimming tablets
BMJ current issue - Oct 24, 2008 11:09 AM

Friday, 24 October 2008

Latest diabetes articles in Big 4

Access
BMJ - current paper copy in library, electronic access 3 months delay - NHS Athens
Lancet - electronic access 2 months delay - NHS Athens
JAMA - current electronic access - NHS Athens
NEJM - current paper copy in library, partial electronic access to recent articles - no password, full text electronic access - 3 months delay - NHS Athens


[Case Report] Shortness of breath, fever—and pain in both legs
...poorly controlled diabetes came to our emergency department with a 1-week history of pain in both legs and shortness of breath, accompanied by fever, chills, and sweating. He had no recent leg injury, and no history of clotting disorder.
The Lancet - 10:39 (4 hours ago)

[NEWS] Children's vitamin D intake should be doubled, US paediatricians say
BMJ current issue - 20 Oct 2008 (4 days ago)

[EDITORIALS] Tight control of blood glucose and cardiovascular disease
BMJ current issue - 17 Oct 2008 12:43

[Articles] Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials
...type 1 diabetes.
The Lancet - 17 Oct 2008 09:47

[Comment] DIRECT new treatments for diabetic retinopathy
...type 2 diabetes into daily placebo or 32 mg candesartan, an angiotensin II receptor blocker). The study recruited from 309 worldwide sites, and followed up patients for 4 years. The investigators report on prevention and progression of diabetic retinopathy in type 1 diabetes (respectively: DIRECT-Prevent 1, n=1421; DIRECT-Protect 1, n=1905), and...
The Lancet - 17 Oct 2008 09:47

[Articles] Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial
...type 2 diabetes.
The Lancet - 17 Oct 2008 09:47

[RESEARCH] The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease
...patients with diabetes mellitus and asymptomatic peripheral arterial disease. Design Multicentre, randomised, double blind, 2x2 factorial, placebo controlled trial. Setting 16 hospital centres in Scotland, supported by 188 primary care groups. Participants 1276 adults aged 40 or more with type 1 or type 2 diabetes and an ankle brachial pressure ...
BMJ current issue - 17 Oct 2008 01:00

[EDITORIALS] Aspirin for prevention of cardiovascular events
BMJ current issue - 17 Oct 2008 01:00

[PRACTICE] Aspirin in type 2 diabetes: is there any evidence base?
BMJ current issue - 16 Oct 2008 13:54

[CLINICAL REVIEW] Obesity in children. Part 1: Epidemiology, measurement, risk factors, and screening
BMJ current issue - 15 Oct 2008 16:45

[NEWS] Half of patients given exercise prescriptions are more active a year later
BMJ current issue - 15 Oct 2008 12:39

BOOK AND MEDIA REVIEWS: Metabolic Syndrome and Psychiatric Illness: Interactions, Pathophysiology, Assessment and Treatment
JAMA current issue - 14 Oct 2008 21:36

MEDICAL NEWS & PERSPECTIVES: JAMA, National University Health System, Singapore, Host Diabetes, Obesity Meeting
JAMA current issue - 14 Oct 2008 21:36

[NEWS] Website of experiences with new name hopes to reach more patients
BMJ current issue - 14 Oct 2008 12:42

Friday, 12 September 2008

Diabetes Technology and Therapeutics, Vol 10, Part 5

We do not have full text access to this journal. Recent articles are available via inter-library loan. Please contact the library if you would like to order an article.

Article Title:
Long - Acting Insulin Analogs Versus Human Insulins
Author(s):
Garg , Satish K . ; Naik , Ramachandra G .
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
331-332
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[article] [author(s)]

Article Title:
Beyond the Era of NPH Insulin - Long - Acting Insulin Analogs : Chemistry , Comparative Pharmacology , and Clinical Application
Author(s):
Owens , D . R . ; Bolli , G . B .
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
333-349
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Article Title:
Validation of the SoloSTAR Insulin Pen
Author(s):
Schwartz , Sherwyn ; Vlajnic , Aleksandra
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
351-357
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Article Title:
Dose Accuracy Comparison Between SoloSTAR and FlexPen at Three Different Dose Levels
Author(s):
Penfornis , Alfred ; Horvat , Kristian
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
359-362
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[article] [author(s)]

Article Title:
Comparison of Gliclazide with Insulin as Initial Treatment Modality in Newly Diagnosed Type 2 Diabetes
Author(s):
Chandra , Satish T . ; Priya , Gagan ; Khurana , Madan L . ; Jyotsna , Viveka P . ; Sreenivas , V . ; Dwivedi , Sadanand ; Ammini , Ariachery C .
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
363-368
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Article Title:
Improved Glycemic Control in Intensively Treated Adult Subjects with Type 1 Diabetes Using Insulin Guidance Software
Author(s):
Garg , Satish K . ; Bookout , Tevin R . ; McFann , Kim K . ; Kelly , William C . ; Beatson , Christie ; Ellis , Samuel L . ; Gutin , Raymond S . ; Gottlieb , Peter A
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
369-375
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Article Title:
Sensor - Augmented Insulin Pump Therapy : Results of the First Randomized Treat - to - Target Study
Author(s):
Hirsch , Irl B . ; Abelseth , Jill ; Bode , Bruce W . ; Fischer , Jerome S . ; Kaufman , Francine R . ; Mastrototaro , John ; Parkin , Christopher G . ; Wolpert , Howard A . ; Buckingham , Bruce A .
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
377-383
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Article Title:
The Accuracy and Efficacy of Real - Time Continuous Glucose Monitoring Sensor in Patients with Type 1 Diabetes
Author(s):
Mastrototaro , John ; Shin , John ; Marcus , Alan ; Sulur , Giri ; for the STAR 1 Clinical Trial Investigators
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
385-390
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Article Title:
Pramlintide Reduces the Risks Associated with Glucose Variability in Type 1 Diabetes
Author(s):
Kovatchev , Boris P ; Crean , John ; McCall , Anthony
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
391-396
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Article Title:
Prevalence of Albuminuria and Cardiovascular Risk Profile in a Referred Cohort of Patients with Type 2 Diabetes : An Asian Perspective
Author(s):
Pan , C . Y . ; Ho , L . T . ; Soegondo , S . ; Prodjosudjadi , W . ; Suwanwalaikorn , S . ; Lim , S . C . ; Chan , T . M . ; Chow , K . W . Steven ; Thoenes , M . ; Choi , D . S . ; on behalf of the DEMAND Study Investigators
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
397-403
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Article Title:
Effects of Chromium Picolinate on Food Intake and Satiety
Author(s):
Anton , Stephen D . ; Morrison , Christopher D . ; Cefalu , William T . ; Martin , Corby K . ; Coulon , Sandra ; Geiselman , Paula ; Han , Hongmei ; White , Christy L . ; Williamson , Donald A .
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
405-412
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Article Title:
Role of Emerging New Technologies
Author(s):
Garg , Satish K
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
413-414
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[article] [author(s)]

Article Title:
Comments on Evaluation of Five Glucose Meters by Thomas et al .
Author(s):
Simmons , David A
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
415
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Article Title:
Response to Simmons
Author(s):
Kane , Michael P . ; Hamilton , Robert A .
ISSUE:
2008 ; VOL 10 ; PART 5 (2008/10/01)
Access:
Diabetes Technology and Therapeutics
Page:
417
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Article Title:
Clinical Application of Emerging Sensor Technologies in Diabetes Management : Consensus Guidelines for Continuous Glucose Monitoring ( CGM )
Author(s):
Hirsch , Irl B . ; Armstrong , Dana ; Bergenstal , Richard M . ; Buckingham , Bruce ; Childs , Belinda P . ; Clarke , William L . ; Peters , Anne ; Wolpert , Howard
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
232-246
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Article Title:
Initiating Insulin Therapy in Type 2 Diabetes : Benefits of Insulin Analogs and Insulin Pens
Author(s):
Brunton , Stephen
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
247-256
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Article Title:
Progress Toward an In Vivo Surface - Enhanced Raman Spectroscopy Glucose Sensor
Author(s):
Lyandres , Olga ; Yuen , Jonathan M . ; Shah , Nilam C . ; VanDuyne , Richard P . ; Walsh , Joseph T . ; Glucksberg , Matthew R .
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
257-265
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Article Title:
The Accuracy of the Guardian® ; RT Continuous Glucose Monitor in Children with Type 1 Diabetes
Author(s):
The Diabetes Research in Children Network ( DirecNet ) Study Group
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
266-272
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Article Title:
Reduced Weight Gain with Insulin Detemir Compared to NPH Insulin Is Not Explained by a Reduction in Hypoglycemia
Author(s):
Davies , Melanie J . ; Derezinski , Tadeusz ; Pedersen , Claus Bang ; Clauson , Per
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
273-277
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Article Title:
Influence of Diabetes on the Validity Glaucoma Screening by Frequency Doubling Perimetry : A Hospital - Based Study in Oman
Author(s):
Khandekar , Rajiv ; Zutshi , Rajiv ; Ali , Mohammed ; Raisi , Abdulatif Al ; Dass , Henry
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
278-282
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Article Title:
Modeling Glucose and Water Dynamics in Human Skin
Author(s):
Groenendaal , W . ; Schmidt , K . A . ; von Basum , G . ; van Riel , N . A . W . ; Hilbers , P . A . J .
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
283-293
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Article Title:
The Effects of Magnetic Field on the Biomechanics Parameters of Soleus and Extensor Digitorum Longus Muscles in Rats with Streptozotocin - Induced Diabetes
Author(s):
Pelit , A . ; è ; Ozaykan , B . ; Tuli , A . ; Demirkazik , A . ; Emre , M . ; Gè ; unay , I .
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
294-298
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[article] [author(s)]

Article Title:
Patient Acceptance and Issues of Education of Two Durable Insulin Pen Devices
Author(s):
Asakura , Toshinari ; Seino , Hiroaki ; Jensen , Klaus H .
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
299-304
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Article Title:
Immunogenicity of Human and Bovine Insulin in Type 1 Diabetes Mellitus Patients
Author(s):
Himanshu , M . ; Bhat , Chetan B . ; Ramchandran , Sarita ; Bhat , K . Geetha ; Kumar , Prasanna K . M .
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
305-309
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[article] [author(s)]

Article Title:
JDRF Randomized Clinical Trial to Assess the Efficacy of Real - Time Continuous Glucose Monitoring in the Management of Type 1 Diabetes : Research Design and Methods
Author(s):
JDRF CGM Study Group
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
310-321
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[article] [author(s)]

Article Title:
Dosing Accuracy with a Novel Pen Device ( SoloSTAR® ; ) as Performed by Patients with Diabetes in a Clinical Setting
Author(s):
Hermanns , Norbert ; Kulzer , Bernhard ; Haak , Thomas
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
322-327
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Article Title:
Torcetrapib as Potential Treatment of Low High - Density Lipoprotein Cholesterol : No Longer a Pipe Dream ?
Author(s):
Ahmed , Mohamed H
ISSUE:
2008 ; VOL 10 ; PART 4 (2008/08/01)
Access:
Diabetes Technology and Therapeutics
Page:
328-329
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[article] [author(s)]

Friday, 29 August 2008

Recent Big 4 diabetes articles

[Department of Error] Department of Error
...type 2 diabetes on oral hypoglycaemic agents (APOLLO): an open randomised controlled trial. Lancet 2008; 371: 1073–84—In this Article (March 29), the fifth line from the bottom of the panel (p 1075) should have read: “≤5·5 mmol/L: no further titration”. The second sentence of the footnote to table 2 (p 1079) should have read: “Fasting blood gluc...
The Lancet - 10:40 (1 hour ago)


[Correspondence] Intensive insulin therapy in patients with type 2 diabetes – Authors' reply
...latent autoimmune diabetes in adults in our population. Although there is no formal consensus regarding diagnostic criteria, the disorder is generally defined as GAD antibody positivity in adult diabetic patients who do not initially (for at least 6 months) require insulin. Usually patients with latent autoimmune diabetes have a low body-mass in...
The Lancet - 10:40 (1 hour ago)


[Correspondence] Intensive insulin therapy in patients with type 2 diabetes
...type 2 diabetes (May 24, p 1573) is an exciting prospect.
The Lancet - 10:40 (1 hour ago)


[Correspondence] Intensive insulin therapy in patients with type 2 diabetes
Jianping Weng and colleagues are to be commended for building a concept that could change clinical practice. However, their conclusions need some clarification.
The Lancet - 10:40 (1 hour ago)


CORRESPONDENCE: Widespread Amyloid Deposition in Transplanted Human Pancreatic Islets
...type 1 diabetes mellitus, diagnosed at 16 years of age, in ...
New England Journal of Medicine - 27 Aug 2008 (2 days ago)



CARING FOR THE CRITICALLY ILL PATIENT: Benefits and Risks of Tight Glucose Control in Critically Ill Adults: A Meta-analysis
...The American Diabetes Association and Surviving Sepsis Campaign recommend tight glucose control in critically ill patients based largely on 1 trial that shows decreased mortality in a surgical intensive care unit. Because similar studies report conflicting results and tight glucose control can cause dangerous hypoglycemia, the data underlying th...
JAMA current issue - 26 Aug 2008 (3 days ago)


[RESEARCH] Role of blood pressure in development of early retinopathy in adolescents with type 1 diabetes: prospective cohort study
...type 1 diabetes. Design Prospective cohort study. Setting Diabetes Complications Assessment Service at the Children’s Hospital at Westmead, Sydney, Australia. Participants 1869 patients with type 1 diabetes (54% female) screened for retinopathy with baseline median age 13.4 (interquartile range 12.0-15.2) years, duration 4.9 (3.1-7.0) years, and...
BMJ current issue - 26 Aug 2008 (3 days ago)


[EDITORIALS] Complications of type 1 diabetes in adolescents
BMJ current issue - 26 Aug 2008 (3 days ago)


[NEWS] Diabetes care needs to focus more on ethnic inequalities, say experts
BMJ current issue - 22 Aug 2008 16:46

[PRACTICE] Should we prescribe diuretics for patients with prediabetes and hypertension?
BMJ current issue - 21 Aug 2008 14:44


LETTERS: Insulin Therapy and Lipid Overload in Type 2 Diabetes--Reply
JAMA current issue - 19 Aug 2008 21:44

LETTERS: Insulin Therapy and Lipid Overload in Type 2 Diabetes
JAMA current issue - 19 Aug 2008 21:44

LETTERS: Pioglitazone vs Glimepiride in the PERISCOPE Trial
JAMA current issue - 19 Aug 2008 21:44


EDITORIAL: Environmental Arsenic Exposure and Diabetes
JAMA current issue - 19 Aug 2008 21:44

LETTERS: Pioglitazone vs Glimepiride in the PERISCOPE Trial--Reply
JAMA current issue - 19 Aug 2008 21:44



LETTERS: Pioglitazone vs Glimepiride in the PERISCOPE Trial
JAMA current issue - 19 Aug 2008 21:44


LETTERS: Insulin Therapy and Lipid Overload in Type 2 Diabetes
JAMA current issue - 19 Aug 2008 21:44


PRELIMINARY COMMUNICATION: Arsenic Exposure and Prevalence of Type 2 Diabetes in US Adults
...related to diabetes development, but the effect of exposure to low to moderate levels of inorganic arsenic on diabetes risk is unknown. In contrast, arsenobetaine, an organic arsenic compound derived from seafood intake, is considered nontoxic. Objective To investigate the association of arsenic exposure, as measured in urine, with the prevalen...
JAMA current issue - 19 Aug 2008 21:44

[Seminar] Acute myocardial infarction
...epidemic of diabetes and obesity in the developed world and the transition from infectious diseases to cardiovascular disease in the developing world will place an increasing demand on health-care infrastructures required to deliver time-dependent and resource-intensive care. This Seminar discusses the underlying pathophysiology, evolving perspe...
The Lancet - 15 Aug 2008 11:00

[Articles] Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial
...or with diabetes with end-organ damage.
The Lancet - 15 Aug 2008 11:00

CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 25-2008 -- A 43-Year-Old Man with Fatigue and Lesions in the Pituitary and Cerebellum
...Diabetes insipidus, hypogonadism, and hypothyroidism had developed beginning 9 years earlier, and lesions had been detected in the region of the pituitary stalk and in the cerebellum. He was treated with glucocorticoids for suspected neurosarcoidosis, but fatigue, ataxia, and neurologic symptoms worsened. Computed tomography of the chest and abd...
New England Journal of Medicine - 13 Aug 2008 22:25

[CORRECTIONS] Evidence shows higher long term risks from gestational diabetes
BMJ current issue - 6 Aug 2008 17:36

Basal insulin glargine vs prandial insulin lispro in type 2 diabetes
Reinhard Bretzel and colleagues (March 29, p 1073) compared once-daily insulin glargine with thrice-daily prandial insulin lispro as add-on therapy to continued oral hypoglycaemic agents. Although glycosylated haemoglobin did not differ between regimens, the overall incidence of hypoglycaemic events was four times higher with insulin lispro than wi...
The Lancet - 1 Aug 2008 11:15

Basal insulin glargine vs prandial insulin lispro in type 2 diabetes – Authors' reply
Sabine Arnolds and Klaus Rave state that the higher hypoglycaemic rate in the lispro group than in the glargine group was potentiated by the presence of glimepiride. However, the relative frequencies of hypoglycaemic events by hour of day showed a similar distribution profile, with peaks at 2 pm for lispro and 3 pm for glargine. A further explanati...
The Lancet - 1 Aug 2008 11:15

Friday, 1 August 2008

National Prescribing Centre's 'Week in Review' 4/7/08

NPCi Blog http://www.npci.org.uk/blog/
· MeReC Rapid Review: Is aliskiren plus losartan renoprotective in patients with type 2 diabetes and nephropathy? http://www.npci.org.uk/blog/?p=160

InfoPOEMs: http://www.essentialevidenceplus.com/
· Metformin effective for gestational diabetes http://www.essentialevidenceplus.com/infopoems/dailyInfoPOEM.cfm?view=121866

National electronic Library for Medicines (NeLM): http://www.nelm.nhs.uk
· FDA panel says diabetes drugs need cardiovascular risk studies http://www.nelm.nhs.uk/Record%20Viewing/vR.aspx?id=594929

Friday, 18 July 2008

Latest Diabetes News from the National Library for Health

MeReC Monthly (June 2008): Self-monitoring in type 2 diabetes
via NeLM news - Diabetes on 7/7/08
The latest edition of MeReC Monthly reviews the use of routine self-monitoring of blood glucose (SMBG), noting that two recent studies (ESMON and DiGEM economic analysis) have reinforced the view that it is unlikely to be beneficial in patients with type 2 diabetes who are not treated with insulin and may worsen quality of life and waste NHS resources. Therefore it should be reserved for patients treated with insulin and for non-insulin treated patients in specific circumstances, as recommended in recent NICE guidance on type 2 diabetes (see link).

SMC accepts restricted use of Eucreas tablets (vildagliptin 50mg + metformin 850mg or 1000mg) for type 2 diabetes
via NeLM news - Diabetes 7/7/08
Following a review of an abbreviated submission (used for new formulations at same or lesser cost, and new tablet strength or size), the Scottish Medicines Consortium (SMC) has accepted for restricted use within NHS Scotland, Eucreas® tablets (vildagliptin 50mg/metformin 850mg and vildagliptin 50mg /metformin 1000mg). ...

Meta-analysis: Pregabalin for painful diabetic neuropathy
via NeLM news - Diabetes on 6/7/08
Pregabalin is effective for treatment of painful diabetic neuropathy across its usual dose range, according to a meta-analysis sponsored by the drug's manufacturer and part-authored by company employees. A number of controlled trials have been carried out with pregabalin in patients with painful diabetic neuropathy, however they have used different dose regimens: this analysis was carried out to evaluate the drug's efficacy and safety in this condition at all effective doses....

DTB: exenatide (Byetta), sitagliptin (Januvia), and vildagliptin (Galvus) for type 2 diabetes
via NeLM news - Diabetes on 6/7/08
The July edition of the Drug and Therapeutics Bulletin (DTB) features a review of three new treatments for type 2 diabetes: exenatide (Byetta®), sitagliptin (Januvia®), and vildagliptin (Galvus®). It discusses the incretins and glucose metabolism, examines the trial data and its limitations, and looks at national guidelines....

FDA panel says diabetes drugs need cardiovascular risk studies
via NeLM news - Diabetes on 2/7/08
PharmaTimes reports that the US Food and Drug Administration’s (FDA) Endocrinologic and Metabolic Drugs Advisory Committee has advised US regulators they should insist that studies on new diabetes treatments include much more data on the potential heart risks of the treatments....

FDA to consider necessity of cardiovascular studies for diabetes drugs
via NeLM news - Diabetes on 30/6/08
According to a report in the Wall Street Journal, the US FDA is summoning a panel of experts to consider whether pharmaceutical companies should be required to study the cardiovascular effects of diabetes drugs prior to approval. The report points out that cardiovascular endpoints are relatively rare and therefore large, long-term studies would be required to demonstrate any statistically significant effects; this could slow the development of new drugs and would increase costs.

FDA approves PrandiMet (repaglinide and metformin) for type 2 diabetes
via NeLM news - Diabetes on 24/6/08
According to BioSpace, the FDA has approved PrandiMet™ (repaglinide and metformin) tablets as an adjunct to diet and exercise to improve glycaemic control in adults with type 2 diabetes mellitus who are already treated with a meglitinide [the drug class that repaglinide belongs to] and metformin or who have inadequate glycaemic control on a meglitinide alone or metformin alone. Please see the link above for details.

Benefits of intensive glucose control in older type 2 diabetics limited by co-morbidity
via NeLM news - Diabetes on 30/6/08
A decision analysis study suggests that for older patients with type 2 diabetes, intensive blood glucose control becomes less useful with increasing co-morbidity and functional impairment; chronological age alone, however, was not useful for predicting benefit. Intensive control of blood glucose has been shown to be beneficial in type 1 diabetes, and may also improve outcomes in type 2 diabetes....

25 June 2008 - My life
via NLH Diabetes Specialist Library Whats New by Diane Clay on 25/6/08
How to manage your diabetes as a young adult, moving away from home, taking control of your life


NPC iblog: Putting blood glucose control in type 2 diabetes into perspective
via NeLM news - Diabetes on 16/6/08
The National Prescribing Centre have published an iblog discussing a “Perspective” article published in the New England Journal of Medicine, that discusses the implications of ACCORD and ADVANCE studies, alongside some other major clinical studies that evaluated the benefits of reducing risk factors, such as blood lipids, blood pressure and blood glucose levels on preventing cardiovascular (CV) disease....

Antipsychotic agents and diabetes: meta-analysis plus study data on aripiprazole
via NeLM news - Diabetes by nelm@gstt.nhs.uk on 15/6/08
Second-generation antipsychotic drugs are associated with a small increase in risk of diabetes compared to first-generation drugs, according to a meta-analysis, although retrospective analysis of data from a clinical trial suggests that an increased risk with aripiprazole may be less likely....

15 June 2008 - Interesting new diabetes papers April 2008
via NLH Diabetes Specialist Library Whats New on 15/6/08
The latest edition of Dr Roger Gadsbys bulletin is now available

11 June 2008 - Diabetic retinopathy screening
via NLH Diabetes Specialist Library Whats New on 11/6/08
Statement published by the Department of Health on 3 April 2008

11 June 2008 - Joint Position Statement - Integrated Care in the Reforming NHS
via NLH Diabetes Specialist Library Whats New on 11/6/08
A joint publication by Diabetes UK, the Association of British Clinical Diabetologists (ABCD), the Primary Care Diabetes Society (PCDS), Community Diabetes Consultants (CDC) and the RCN Diabetes Nursing Forum issued in December 2007

Friday, 11 July 2008

Diabetes Care

Diabetes Care is available free to NHS staff 3 months after publication. Articles with links provided are available earlier. You can also order individual articles using the Inter-Library Loan system if you need them quicker. Please contact the library for further details.

Volume 31, Number 7

Clinical Care/Education/Nutrition/Psychosocial Research

Isolated Hyperglycemia at 1 Hour on Oral Glucose Tolerance Test in Pregnancy Resembles Gestational Diabetes Mellitus in Predicting Postpartum Metabolic Dysfunction
Ravi Retnakaran, Ying Qi, Mathew Sermer, Philip W. Connelly, Bernard Zinman, and Anthony J.G. Hanley

Effect of Supervised Progressive Resistance-Exercise Training Protocol on Insulin Sensitivity, Glycemia, Lipids, and Body Composition in Asian Indians With Type 2 Diabetes
Anoop Misra, Narendra K. Alappan, Naval K. Vikram, Kashish Goel, Nidhi Gupta, Kanchan Mittal, Suryaprakash Bhatt, and Kalpana Luthra

Long-Term Outcome and Disability of Diabetic Patients Hospitalized for Diabetic Foot Ulcers: A 6.5-year follow-up study
Edouard Ghanassia, Laetitia Villon, Jean-François Thuan dit Dieudonné, Catherine Boegner, Antoine Avignon, and Ariane Sultan

The Prospective Contribution of Hostility Characteristics to High Fasting Glucose Levels: The moderating role of marital status
Biing-Jiun Shen, Amanda J. Countryman, Avron Spiro, III, and Raymond Niaura

Weight Loss Strategies Associated With BMI in Overweight Adults With Type 2 Diabetes at Entry Into the Look AHEAD (Action for Health in Diabetes) Trial
Hollie A. Raynor, Robert W. Jeffery, Andrea M. Ruggiero, Jeanne M. Clark, Linda M. Delahanty for the Look AHEAD (Action for Health in Diabetes) Research Group

Adjust to Target in Type 2 Diabetes: Comparison of a simple algorithm with carbohydrate counting for adjustment of mealtime insulin glulisine
Richard M. Bergenstal, Mary Johnson, Margaret A. Powers, Alan Wynne, Aleksandra Vlajnic, Priscilla Hollander, and Marc Rendell

Intake of Fruit, Vegetables, and Fruit Juices and Risk of Diabetes in Women
Lydia A. Bazzano, Tricia Y. Li, Kamudi J. Joshipura, and Frank B. Hu

Dietary Behaviors Predict Glycemic Control in Youth With Type 1 Diabetes
Sanjeev N. Mehta, Lisa K. Volkening, Barbara J. Anderson, Tonja Nansel, Jill Weissberg-Benchell, Tim Wysocki, Lori M.B. Laffel for the Family Management of Childhood Diabetes Study Steering Committee

Long-Term Follow-Up of Oral Glucose Tolerance Test–Derived Glucose Tolerance and Insulin Secretion and Insulin Sensitivity Indexes in Subjects With Glucokinase Mutations (MODY2)
Delphine Martin, Christine Bellanné-Chantelot, Inge Deschamps, Philippe Froguel, Jean-Jacques Robert, and Gilberto Velho

Improving Treatment of Depression Among Latinos With Diabetes Using Project Dulce and IMPACT
Todd P. Gilmer, Chris Walker, Elizabeth D. Johnson, Athena Philis-Tsimikas, and Jürgen Unützer

Randomized Efficacy Trial of Early Preconception Counseling for Diabetic Teens (READY-Girls)
Denise Charron-Prochownik, Margaret Ferons-Hannan, Susan Sereika, and Dorothy Becker

Epidemiology/Health Services Research

Association Between Renal Failure and Foot Ulcer or Lower-Extremity Amputation in Patients With Diabetes
David J. Margolis, Ole Hofstad, and Harold I. Feldman

Trends in Diabetes, High Cholesterol, and Hypertension in Chronic Kidney Disease Among U.S. Adults: 1988–1994 to 1999–2004
Caroline S. Fox and Paul Muntner

Dietary Patterns, Insulin Resistance, and Incidence of Type 2 Diabetes in the Whitehall II Study
Sarah A. McNaughton, Gita D. Mishra, and Eric J. Brunner

Longitudinal Association of Glucose Metabolism With Retinopathy: Results from the Australian Diabetes Obesity and Lifestyle (AusDiab) study
Robyn J. Tapp, Gabriella Tikellis, Tien Y. Wong, C. Alex Harper, Paul Z. Zimmet, Jonathan E. Shaw on behalf of the Australian Diabetes Obesity and Lifestyle Study Group

Plasma Carotenoids and Onset of Dysglycemia in an Elderly Population: Results of the Epidemiology of Vascular Ageing Study
Tasnime N. Akbaraly, Annick Fontbonne, Alain Favier, and Claudine Berr

Relationship Between Risk Factors and Mortality in Type 1 Diabetic Patients in Europe: The EURODIAB Prospective Complications Study (PCS)
Sabita S. Soedamah-Muthu, Nish Chaturvedi, Daniel R. Witte, Lynda K. Stevens, Massimo Porta, John H. Fuller for the EURODIAB Prospective Complications Study Group

Burden and Rates of Treatment and Control of Cardiovascular Disease Risk Factors in Obesity: The Framingham Heart Study
Esther A. Molenaar, Shih-Jen Hwang, Ramachandran S. Vasan, Diederick E. Grobbee, James B. Meigs, Ralph B. D'Agostino, Sr., Daniel Levy, and Caroline S. Fox

Periodontal Disease and Incident Type 2 Diabetes: Results from the First National Health and Nutrition Examination Survey and its Epidemiologic Follow-Up Study
Ryan T. Demmer, David R. Jacobs, Jr., and Moïse Desvarieux

Differences in the Pattern of Antibiotic Prescription Profile and Recurrence Rate for Possible Urinary Tract Infections in Women With and Without Diabetes
Caroline Schneeberger, Ronald P. Stolk, J. Hans DeVries, Peter M. Schneeberger, Ron M. Herings, and Suzanne E. Geerlings

Inflammation Among Women With a History of Gestational Diabetes Mellitus and Diagnosed Diabetes in the Third National Health and Nutrition Examination Survey
Catherine Kim, Yiling J. Cheng, and Gloria L. Beckles

Sex Disparities in the Treatment and Control of Cardiovascular Risk Factors in Type 2 Diabetes
Ioanna Gouni-Berthold, Heiner K. Berthold, Christos S. Mantzoros, Michael Böhm, and Wilhelm Krone

Pathophysiology/Complications

Trends in High-Risk HLA Susceptibility Genes Among Colorado Youth With Type 1 Diabetes
Kendra Vehik, Richard F. Hamman, Dennis Lezotte, Jill M. Norris, Georgeanna J. Klingensmith, Marian Rewers, and Dana Dabelea

Adipose Tissue Lipolysis Is Upregulated in Lean and Obese Men During Acute Resistance Exercise
Athanasios Chatzinikolaou, Ioannis Fatouros, Anatoli Petridou, Athanasios Jamurtas, Alexandra Avloniti, Ioannis Douroudos, George Mastorakos, Christina Lazaropoulou, Ioannis Papassotiriou, Symeon Tournis, Asimina Mitrakou, and Vassilis Mougios

Increased Shear Rate Resistance and Fastest Kinetics of Erythrocyte Aggregation in Diabetes Measured With Ultrasound
Guy Cloutier, Audrey Zimmer, François T.H. Yu, and Jean-Louis Chiasson

Too Much Glucagon, Too Little Insulin: Time course of pancreatic islet dysfunction in new-onset type 1 diabetes
Rebecca J. Brown, Ninet Sinaii, and Kristina I. Rother

Cardiovascular and Metabolic Risk

Global Coronary Heart Disease Risk Assessment of Individuals With the Metabolic Syndrome in the U.S.
Khiet C. Hoang, Heli Ghandehari, Victor A. Lopez, Michael G. Barboza, and Nathan D. Wong

Adipokines and Incident Type 2 Diabetes in an Aboriginal Canadian Population: The Sandy Lake Health and Diabetes Project
Sylvia H. Ley, Stewart B. Harris, Philip W. Connelly, Mary Mamakeesick, Joel Gittelsohn, Robert A. Hegele, Ravi Retnakaran, Bernard Zinman, and Anthony J.G. Hanley

Sex Differences in Diabetes Risk and the Effect of Intensive Lifestyle Modification in the Diabetes Prevention Program
Leigh Perreault, Yong Ma, Sam Dagogo-Jack, Edward Horton, David Marrero, Jill Crandall, Elizabeth Barrett-Connor for the Diabetes Prevention Program

Association of Intrauterine Exposure to Maternal Diabetes and Obesity With Type 2 Diabetes in Youth: The SEARCH Case-Control Study
Dana Dabelea, Elizabeth J. Mayer-Davis, Archana P. Lamichhane, Ralph B. D'Agostino, Jr., Angela D. Liese, Kendra S. Vehik, K.M. Venkat Narayan, Phillip Zeitler, and Richard F. Hamman

Retinol-Binding Protein 4 and Insulin Resistance in Polycystic Ovary Syndrome
Samantha K. Hutchison, Cheryce Harrison, Nigel Stepto, Caroline Meyer, and Helena J. Teede

Insulin Resistance and Hyperinsulinemia: You can't have one without the other
Sun H. Kim and Gerald M. Reaven

Tumor Necrosis Factor- Antagonism Improves Vasodilation During Hyperinsulinemia in Metabolic Syndrome
Manfredi Tesauro, Francesca Schinzari, Valentina Rovella, Domenico Melina, Nadia Mores, Angela Barini, Marco Mettimano, Davide Lauro, Micaela Iantorno, Michael J. Quon, and Carmine Cardillo

Assessment of Aortic Pulse Wave Velocity and Cardiac Diastolic Function in Subjects With and Without the Metabolic Syndrome: HDL cholesterol is independently associated with cardiovascular function
Stijntje D. Roes, Reza Alizadeh Dehnavi, Jos J.M. Westenberg, Hildo J. Lamb, Bart J.A. Mertens, Jouke T. Tamsma, and Albert de Roos

Hyperinsulinemia in African-American Adolescents Compared With Their American White Peers Despite Similar Insulin Sensitivity: A reflection of upregulated β-cell function?
Tamara S. Hannon, Fida Bacha, Yan Lin, and Silva A. Arslanian

Reviews/Commentaries/ADA Statements

Meta-Analysis

Efficacy, Safety, and Tolerability of Pregabalin Treatment for Painful Diabetic Peripheral Neuropathy: Findings from seven randomized, controlled trials across a range of doses
Roy Freeman, Edith Durso-DeCruz, and Birol Emir

Rosiglitazone and Risk of Cancer: A meta-analysis of randomized clinical trials
Matteo Monami, Caterina Lamanna, Niccolò Marchionni, and Edoardo Mannucci Diabetes Care 2008 31: 1455-1460.

Perspectives on the News

Approaches to Treatment of Pre-Diabetes and Obesity and Promising New Approaches to Type 2 Diabetes
Zachary T. Bloomgarden

Editorials

Death to Carbohydrate Counting?
Nichola J. Davis and Judith Wylie-Rosett

Diabetic Medicine

Guest Editorial

Estimated average glucose (eAG): fit for purpose?
Eric S. Kilpatrick

Commentary from Copenhagen on the NICE guideline on management of diabetes and its complications from pre-conception to the postnatal period.Elisabeth R Mathiesen and Peter Damm

Letter

Methodology problems in using eGFR to investigate the prevalence of Renal Anaemia

Postprandial triglyceridaemia in men with impaired fasting glucose, impaired glucose tolerance and diabetes.
R. Oka, K. Yagi, S. Hifumi, S. Miyamoto, H. Mabuchi, M. Yamagishi, Y. Takeda, A. Inazu, A. Nohara, M. Kawashiri and J. Kobayashi

Original articles
Treatment of chronic diabetic foot ulcers with bemiparin: A randomised, triple-blind, placebo controlled, clinical trial M. Rullan, L. Cerdà, G. Frontera, L. Masmiquel and J. Llobera

Care Delivery

Glycaemic control and diabetes care utilization in young adults with Type 1 diabetes
Carina Sparud-Lundin, Ingbritt Öhrn, Ella Danielson Gun Forsander

A Comparison of Diabetes Clinics with Different Emphasis on Routine Care, Complications Assessment and Shared Care
NW Cheung DK Yue MA Kotowicz PA Jones and JR Flack

Treatment

Safety and Efficacy of Glargine compared with NPH Insulin for the Treatment of Type 2 Diabetes: A Meta-analysis of Randomized Controlled Trials
Lydia A. Bazzano, MD, PhD, Lauren J. Lee, PharmD, MS, Lizheng Shi, MsPharm, PhD, Kristi Reynolds, PhD, Jeffrey A. Jackson, MD and Vivian Fonseca, MD
Metabolism

Longitudinal Screening of Serum Lipids in Children and Adolescents with Type 1 Diabetes in a UK Clinic Population
Julie A Edge Tim James Brian Shine

Point-of-care testing as a tool for screening for diabetes and prediabetes.
Elaine Rush, Nic Crook and David Simmons

Variability of lipids in patients with type 2 diabetes taking statin treatment: implications for target setting.
Thozhukat Sathyapalan, Stephen L. Atkin, Eric S. Kilpatrick,

Effects of Fat Supplementation on Glycaemic Response and Gastric Emptying in Adolescents with Type 1 Diabetes
M Lodefalk, J Åman and P Bang

Metabolism
Childhood Body Mass Index (BMI), breastfeeding and risk of type 1 diabetes: findings from a longitudinal national birth cohort
Russell M Viner Peter C Hindmarsh Brent Taylor and Timothy J Cole

Combined association of maternal and paternal family history of diabetes on plasma leptin and adiponectin in overweight Hispanic children
Koebnick C, Kelly LA, Lane CJ, Roberts CK, Shaibi GQ, Toledo-Corral CM, Davis JN, Weigensberg MJ and Goran MI

Short reports

HbA1c: the case for using estimated average glucose (eAG)
Philip Home

Hypertriglyceridaemia is associated with an increased likelihood of albuminuria in extreme duration (> 50 years) Type 1 diabetes Manuscript DME-2008-00150C Daousi, SC Bain, AH Barnett and GV Gill

Plasma triglycerides and LDL-cholesterol are related in a parabolic fashion in the general population and patients with type 2 diabetes mellitus: long-term follow-up results from the Hoorn study
M.C.G.J. Brouwers, J.M. Dekker, M.M.J. van Greevenbroek, C.J.H. van der Kallen, R.J. Heine, T.W.A. de Bruin and C.D.A. Stehouwer

Review

NICE guidance on Diabetes in pregnancy: management of diabetes and its complications from pre-conception to the postnatal period. NICE clinical guideline 63. London, March 2008.

Case Report

Renal Failure and Rhabdomyolysis Associated With Sitagliptin and Simvastatin Use
David P. Kao, Holbrook E Kohrt, John Kugler

Psychological aspects

A LONGITUDINAL STUDY OF AFFECTIVE AND ANXIETY DISORDERS, DEPRESSIVE AFFECT AND DIABETES DISTRESS in ADULTS WITH TYPE 2 DIABETES
Lawrence Fisher, Marilyn M. Skaff, Joseph T. Mullan, Patricia Arean, Russell Glasgow and Umesh Masharani

PREVALENCE AND REASONS FOR INSULIN REFUSAL in BANGLADESHI PATIENTS WITH POORLY CONTROLLED TYPE 2 DIABETES IN EAST LONDON
Hamida Khan, Shawarna S Lasker, Tahseen A Chowdhury
Psychological aspects

Symptoms of Depression Prospectively Predict Poorer Self-Care in Patients with Type 2 Diabetes
JS Gonzalez, SA Safren, LM Delahanty, E Cagliero, DJ Wexler, JB Meigs and RW Grant

The personal cost of diabetic foot disease in developing world a study from Pakistan.
Syed Mansoor Ali, Aslam Fareed, Syed Mujahid Humail, Abdul Basit, Muhammad Yakoob Ahmedani, Asher Fawwad, M. Phil and Zahid Miyan.
Treatment

Diabetes, Obesity and Metabolism

Volume 10, Issue 7, July 2008

Review Articles

Sudden cardiac death: influence of diabetes
P. M. Spooner
pages 523–532

Cardiovascular drugs as antidiabetic agents: evidence for the prevention of type 2 diabetes
D. P. Macfarlane, K. R. Paterson M. Fisher
pages 533–544


Original Articles

Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency
J. C. N. Chan, R. Scott, J. C. Arjona Ferreira, D. Sheng, E. Gonzalez, M. J. Davies, P. P. Stein, K. D. Kaufman, J. M. Amatruda D. Williams-Herman
pages 545–555

Overnight CSII as supplement to oral antidiabetic drugs in Type 2 diabetes
T. Parkner, M. K. Møller, J. W. Chen, T. Laursen, C. Jørgensen, J. S. Smedegaard, T. Lauritzen J. S. Christiansen
pages 556–563

Pioglitazone attenuates fatty acidinduced oxidative stress and apoptosis in pancreatic -cells
Y. Saitoh, C. Chun-ping, K. Noma, H. Ueno, M. Mizuta M. Nakazato
pages 564–573

Salacia oblonga root decreases cardiac hypertrophy in Zucker diabetic fatty rats: inhibition of cardiac expression of angiotensin II type 1 receptor
T. H. Huang, L. He, Q. Qin, Q. Yang, G. Peng, M. Harada, Y. Qi, J. Yamahara, B. D. Roufogalis Y. Li
pages 574–585

Improved metabolic control by Ipomoea batatas (Caiapo) is associated with increased adiponectin and decreased fibrinogen levels in type 2 diabetic subjects
B. Ludvik, M. Hanefeld, G. Pacini
pages 586–592

Research Letters

Patient-reported rating of gastrointestinal adverse effects during treatment of type 2 diabetes with the once-daily human GLP-1 analogue, liraglutide
M. Horowitz, T. Vilsbøll, M. Zdravkovic, M. Hammer, S. Madsbad
pages 593–596

Glimepiride as insulin sensitizer: increased liver and muscle responses to insulin
R. C. T. Mori, S. M. Hirabara, A. E. Hirata, M. M. Okamoto U. F. Machado
pages 596–600

Plasma visfatin is reduced after aerobic exercise in early onset type 2 diabetes mellitus
I. Brema, M. Hatunic, F. Finucane, N. Burns, J. J. Nolan, D. Haider, M. Wolzt, B. Ludvik
pages 600–602